beta-Secretase

Protein Family Details

  Property   Value
 Name beta-Secretase
Family ID 1857_m
First Chain 2ohr (A)
  No of Chains 58
  No of Clusters 2
  No of Rep. Chains 58
  No of Dimensions 2
No of Domain Movements 2

Clusters

Cluster ID Diameter (A) No of Chains Representative Members
1 0.51 46 Extended 1fkn(A)  1fkn(B)  1m4h(A)  1m4h(B)  1sgz(A)  1sgz(B)  1sgz(C)  1sgz(D)  1tqf(A)  1xn2(A)  1xn2(B)  1xn2(C)  1xn2(D)  1xn3(A)  1xn3(B)  1xn3(C)  1xn3(D)  1xs7(D)  1ym2(A)  1ym2(B)  1ym2(C)  1ym4(A)  1ym4(B)  1ym4(C)  2b8l(A)  2b8v(A)  2f3e(A)  2f3e(B)  2f3e(C)  2f3f(A)  2f3f(B)  2f3f(C)  2fdp(A)  2fdp(B)  2fdp(C)  2g94(A)  2g94(B)  2g94(C)  2g94(D)  2hiz(A)  2hiz(B)  2hiz(C)  2hm1(A)  2iqg(A)  2irz(A)  2is0(A) 
2 0.66 12 Extended 1w50(A)  1w51(A)  2of0(A)  2ohk(A)  2ohl(A)  2ohm(A)  2ohn(A)  2ohq(A)  2ohr(A)  2ohs(A)  2oht(A)  2ohu(A) 

Dimensions

Dimension ID Chain 1 Chain 2 Dyndom Run
1 (Vector: v1) 2fdp (C) 2ohr (A) true
2 (Vector: v2) 2ohr (A) 1w50 (A) true

Associated Chains for 1-dimension

Chain ID Protein Name Sequence Length Resolution Cluster ID Projection
2f3e (C) Beta-secretase 1 381 2.11 1 0.08v1
2hiz (C) Beta-secretase 1 373 2.5 1 0.08v1
2f3f (C) Beta-secretase 1 377 2.3 1 0.06v1
1ym2 (A) Beta-secretase 1 376 2.05 1 0.07v1
1ym2 (C) Beta-secretase 1 376 2.05 1 0.08v1
1ym2 (B) Beta-secretase 1 377 2.05 1 0.1v1
1fkn (A) MEMAPSIN 2 391 1.9 1 0.09v1
1fkn (B) MEMAPSIN 2 389 1.9 1 0.08v1
1m4h (A) beta-Secretase 391 2.1 1 0.12v1
1m4h (B) beta-Secretase 389 2.1 1 0.11v1
2g94 (C) Beta-secretase 1 389 1.86 1 0.15v1
2g94 (B) Beta-secretase 1 389 1.86 1 0.13v1
2g94 (A) Beta-secretase 1 389 1.86 1 0.14v1
1xn2 (D) Beta-secretase 1 389 1.9 1 0.13v1
1xn2 (B) Beta-secretase 1 389 1.9 1 0.13v1
1xn3 (C) Beta-secretase 1 389 2 1 0.13v1
1xn3 (D) Beta-secretase 1 389 2 1 0.13v1
1xn2 (C) Beta-secretase 1 389 1.9 1 0.11v1
1xn2 (A) Beta-secretase 1 389 1.9 1 0.12v1
2g94 (D) Beta-secretase 1 389 1.86 1 0.12v1
1xs7 (D) Beta-secretase 1 389 2.8 1 0.11v1
2fdp (A) Beta-secretase 1 373 2.5 1 0.1v1
2hiz (A) Beta-secretase 1 371 2.5 1 0.05v1
1sgz (B) Beta-secretase 389 2 1 0.16v1
1xn3 (B) Beta-secretase 1 389 2 1 0.16v1
1sgz (D) Beta-secretase 389 2 1 0.16v1
1sgz (C) Beta-secretase 389 2 1 0.17v1
1sgz (A) Beta-secretase 389 2 1 0.15v1
1xn3 (A) Beta-secretase 1 389 2 1 0.15v1
1ym4 (A) Beta-secretase 1 379 2.25 1 0.15v1
2fdp (B) Beta-secretase 1 369 2.5 1 0.04v1
2iqg (A) Beta-secretase 1 375 1.7 1 0.05v1
2hm1 (A) Beta-secretase 1 375 2.2 1 0.06v1
1ym4 (C) Beta-secretase 1 379 2.25 1 0.14v1
1ym4 (B) Beta-secretase 1 377 2.25 1 0.15v1
2b8l (A) Beta-secretase 1 379 1.7 1 0.12v1
2b8v (A) Beta-secretase 1 373 1.8 1 0.11v1
2f3e (A) Beta-secretase 1 377 2.11 1 0.08v1
2irz (A) Beta-secretase 1 379 1.8 1 0.11v1
2is0 (A) Beta-secretase 1 379 2.2 1 0.1v1
1w51 (A) BETA-SECRETASE 1 374 2.55 2 0.82v1
2ohl (A) Beta-secretase 1 376 2.65 2 0.88v1
2ohu (A) Beta-secretase 1 376 2.35 2 0.88v1
2ohm (A) Beta-secretase 1 376 2.7 2 0.87v1
1tqf (A) Beta-secretase 1 371 1.8 1 0.14v1
2f3e (B) Beta-secretase 1 377 2.11 1 0.08v1
2f3f (A) Beta-secretase 1 375 2.3 1 0.06v1
2f3f (B) Beta-secretase 1 377 2.3 1 0.06v1
2hiz (B) Beta-secretase 1 372 2.5 1 0.08v1
2ohs (A) Beta-secretase 1 373 2.45 2 0.94v1
2ohr (A) Beta-secretase 1 376 2.25 2 1.0v1
2fdp (C) Beta-secretase 1 374 2.5 1 0

Associated Chains for 2-dimensions

Chain ID Protein Name Sequence Length Resolution Cluster ID Projection
2ohk (A) Beta-secretase 1 376 2.2 2 1.0v1 + 0.77v2
2oht (A) Beta-secretase 1 376 2.3 2 1.03v1 + 0.83v2
2ohq (A) Beta-secretase 1 376 2.1 2 1.0v1 + 0.92v2
2ohn (A) Beta-secretase 1 376 2.15 2 1.0v1 + 0.9v2
2of0 (A) Beta-secretase 1 376 2.25 2 1.02v1 + 0.84v2
1w50 (A) BETA-SECRETASE 1 377 1.75 2 1.0v1 + 1.0v2
2ohr (A) Beta-secretase 1 376 2.25 2 1.0v1