Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-640   ASP-641  6.4 5.7 -31.6 -4.2 101.5 95.5 -1.7
 ASP-641   PHE-642  3.4 2.3 -24.4 1.9 101.3 115.9 -7.6
 PHE-642   GLY-643  1.4 2.3 -32.5 -42.6 75.4 60.8 48.7
 GLY-643   LEU-644  2.6 3.1 31.9 35.6 52.9 95.1 45.4
 LEU-644   ALA-645  4.3 3.8 141.8 -24.7 80.3 68.0 60.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  9.2 11.2 -45.0 22.2 51.3 96.3 20.2
 PRO-663   VAL-664  7.0 8.0 -85.2 -22.4 20.1 50.1 116.3
 VAL-664   LYS-665  7.8 8.2 20.0 -10.0 133.9 134.9 -1.3
 LYS-665   TRP-666  6.4 6.4 6.0 2.4 84.2 76.0 -1.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees