Arachidonate 15-Lipoxygenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-164   GLU-165  6.3 6.5 -18.4 -15.6 88.2 110.0 -3.5
 GLU-165   ARG-166  4.4 5.0 133.2 -52.6 23.8 16.5 241.5
 ARG-166   PHE-167  4.5 5.4 57.6 -62.0 74.8 79.8 -19.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-190   SER-191  28.3 28.9 -27.8 13.1 45.4 21.7 31.3
 SER-191   LEU-192  27.3 28.1 -31.8 0.7 45.1 56.6 67.3
 LEU-192   ASN-193  29.8 30.2 11.5 141.2 80.7 70.7 176.8
 ASN-193   ILE-194  32.6 33.1 32.8 -68.4 98.9 88.7 117.9
 ILE-194   LEU-195  31.5 34.2 172.2 -19.4 112.6 23.7 -295.7
 LEU-195   ALA-196  34.8 35.9 111.9 6.8 72.9 97.2 73.4
 ALA-196   PRO-197  37.1 37.2 1.3 -13.3 56.3 59.4 -19.3
 PRO-197   TRP-198  40.3 40.8 -16.5 20.2 170.5 143.4 15.2
 TRP-198   LYS-199  40.4 41.1 19.4 -20.0 64.2 65.0 0.6
 LYS-199   THR-200  43.9 44.6 42.4 -19.9 47.7 84.7 33.6
 THR-200   LEU-201  44.7 44.5 -36.3 3.4 125.1 134.2 -64.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 SER-592   ILE-593  23.9 23.2 -43.9 37.0 39.9 29.9 19.1
 ILE-593   VAL-594  22.6 21.6 -7.4 -14.2 30.8 48.6 58.5
 VAL-594   TRP-595  24.5 24.0 -31.1 19.7 90.9 107.5 10.2
 TRP-595   GLN-596  22.7 24.4 -3.8 14.4 68.9 87.7 16.5
 GLN-596   LEU-597  19.4 20.8 35.0 -11.2 178.3 146.9 -74.7
 LEU-597   GLY-598  20.2 21.3 -35.0 90.4 63.5 91.3 -14.2
 GLY-598   ARG-599  22.1 24.6 -36.2 24.8 134.8 128.3 -23.7
 ARG-599   ASP-600  22.3 23.9 160.2 158.2 113.9 127.8 54.0
 ASP-600   GLN-601  22.2 23.9 -52.8 28.3 106.5 103.0 -26.6
 GLN-601   PRO-602  19.1 20.7 0.7 -15.6 64.6 111.0 -11.6
 PRO-602   ILE-603  18.8 21.7 1.3 31.8 129.7 145.1 -94.3
 ILE-603   MET-604  19.0 19.4 -67.5 16.8 28.8 47.0 136.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees