Cetuximab Fab Light Chain

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-104   GLU-105  6.7 6.7 0.1 4.6 91.8 89.9 -7.3  GLU-105   LEU-106  3.8 3.6 3.9 -19.4 163.0 161.9 74.9  LEU-106   LYS-107  1.5 1.3 1.9 -3.9 102.7 103.4 -22.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees