Blood Coagulation Factor Xa

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-87   LEU-88  7.2 7.1 -36.4 30.0 14.5 13.5 43.3
 LEU-88   CYS-89  5.8 6.0 -3.2 4.7 75.3 82.0 -6.5
 CYS-89   SER-90  2.6 2.7 10.2 4.7 58.8 58.7 68.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-100   HIS-101  3.8 4.1 5.0 3.6 61.4 60.9 32.5
 HIS-101   GLU-102  4.3 4.5 -10.9 19.7 75.8 72.4 11.3
 GLU-102   GLU-103  7.8 7.7 -8.8 4.3 136.8 141.1 -21.5
 GLU-103   GLN-104  11.1 10.9 -55.1 40.2 54.2 64.4 85.8
 GLN-104   ASN-105  14.6 14.0 1.5 15.4 161.4 173.8 -118.1
 ASN-105   SER-106  12.6 12.5 -4.7 -9.0 57.8 67.6 66.9
 SER-106   VAL-107  11.5 11.5 -5.3 -1.4 112.8 113.4 -18.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees