Cyclin-Dependent Kinase 6

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-160   LEU-161  8.9 8.4 -22.1 11.8 160.3 156.1 -7.9
 LEU-161   ALA-162  7.7 7.6 -15.2 42.9 85.4 85.1 3.2
 ALA-162   ASP-163  4.1 3.9 18.1 -175.3 18.6 33.7 -91.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-180   VAL-181  10.3 7.1 -16.9 176.4 157.1 94.6 113.5
 VAL-181   THR-182  8.1 6.3 102.8 -105.8 57.6 127.6 -9.4
 THR-182   LEU-183  9.6 5.3 57.2 68.9 88.3 130.8 -37.0
 LEU-183   TRP-184  8.2 7.3 -65.8 13.2 88.1 106.9 -7.9
 TRP-184   TYR-185  11.9 10.2 -4.0 -19.9 121.4 124.3 -8.1
 TYR-185   ARG-186  11.6 10.8 -9.0 9.6 68.8 70.8 -1.8
 ARG-186   ALA-187  10.0 10.3 -0.5 -0.8 70.8 71.9 0.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees