Eosinophil-Derived Neurotoxin

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-44   LEU-45  7.6 7.9 -10.1 5.1 92.3 88.7 66.4
 LEU-45   THR-46  8.9 9.5 -10.8 14.3 71.6 71.0 4.5
 THR-46   THR-47  7.6 8.3 28.0 -29.5 156.4 153.0 25.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-75   SER-76  6.5 6.1 -13.6 -32.9 43.9 11.3 482.7
 SER-76   GLN-77  4.5 4.1 62.0 2.0 99.2 99.1 -57.1
 GLN-77   VAL-78  1.2 1.1 0.0 -8.8 74.9 64.4 -64.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-106   TYR-107  3.2 3.0 6.9 -20.8 133.2 132.2 87.1
 TYR-107   ILE-108  4.3 4.5 4.2 -0.6 134.6 139.5 -39.2
 ILE-108   VAL-109  6.4 6.3 7.4 -2.4 143.7 141.3 -35.8
 VAL-109   ALA-110  5.6 5.5 3.5 -7.6 142.3 144.1 32.8
 ALA-110   CYS-111  7.4 7.3 -10.3 7.4 49.9 44.5 7.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-127   VAL-128  3.5 3.5 -2.9 -6.7 65.0 68.6 64.3
 VAL-128   HIS-129  7.1 7.1 -3.6 4.4 130.2 130.2 16.7
 HIS-129   LEU-130  9.0 9.1 -5.6 4.3 154.0 152.8 25.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees