Isocitrate Dehydrogenase [Nadp] Cytoplasmic

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-134   TYR-135  7.8 8.3 -62.7 20.5 93.0 132.2 -105.5
 TYR-135   GLY-136  11.0 10.6 139.8 106.2 147.1 117.1 498.2
 GLY-136   ASP-137  13.5 13.7 44.7 117.1 80.2 63.6 91.7
 ASP-137   GLN-138  16.6 16.5 -133.2 -18.6 126.1 128.3 -815.3
 GLN-138   TYR-139  18.4 18.7 3.1 27.6 15.8 35.0 190.9
 TYR-139   ARG-140  16.6 15.7 16.7 -61.0 71.0 78.9 -105.1
 ARG-140   ALA-141  18.9 16.4 24.8 -22.2 38.8 15.3 30.6
 ALA-141   THR-142  17.8 15.7 4.3 17.8 28.2 65.8 106.5
 THR-142   ASP-143  18.2 18.5 24.2 21.4 59.1 62.3 144.8
 ASP-143   PHE-144  19.4 19.9 16.8 -33.5 69.3 69.6 -74.8
 PHE-144   VAL-145  22.3 23.0 -10.5 -9.2 110.6 120.4 -78.8
 VAL-145   VAL-146  24.4 24.7 -168.9 -167.0 160.2 169.0 135.5
 VAL-146   PRO-147  24.3 24.4 14.4 53.3 79.2 72.8 155.9
 PRO-147   GLY-148  27.7 27.9 -128.5 84.7 167.2 133.5 -260.6
 GLY-148   PRO-149  27.3 27.1 30.0 -6.5 58.0 55.7 78.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-180   GLY-181  15.7 16.7 -3.3 2.4 71.3 83.5 5.9
 GLY-181   MET-182  13.7 14.1 0.9 25.0 31.8 22.9 157.9
 MET-182   TYR-183  10.9 11.9 4.2 9.2 101.2 97.8 -37.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees