Thioredoxin Glutathione Reductase
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-113
GLY-114
6.1
6.1
-2.0
-3.0
17.9
18.6
53.7
GLY-114
GLY-115
5.5
5.6
-12.2
11.8
55.0
57.7
44.2
GLY-115
GLY-116
7.5
7.8
15.7
-21.8
164.8
162.0
145.7
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-117
GLY-118
10.5
10.7
-4.3
-10.5
41.3
40.0
303.0
GLY-118
GLY-119
12.1
12.1
6.8
-0.6
137.0
137.0
46.8
GLY-119
LEU-120
11.2
10.8
4.3
5.2
88.9
82.4
-263.9
LEU-120
ALA-121
13.2
12.9
-1.2
-3.6
104.2
93.3
82.4
ALA-121
ALA-122
15.8
15.7
1.3
0.7
150.0
155.9
-82.4
ALA-122
GLY-123
16.2
15.9
-13.2
9.5
55.9
61.7
109.7
GLY-123
LYS-124
16.0
15.6
-0.4
-5.0
103.2
105.2
46.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-137
TYR-138
6.1
6.2
1.9
1.7
93.5
93.6
13.7
TYR-138
VAL-139
5.2
5.2
-0.1
0.6
43.9
42.4
73.0
VAL-139
GLU-140
4.6
4.7
-3.5
11.5
95.4
97.1
-90.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
TRP-148
GLY-149
7.5
7.6
-0.6
6.9
45.5
46.0
-142.7
GLY-149
LEU-150
8.9
9.2
-0.3
-8.8
72.3
69.5
114.8
LEU-150
GLY-151
9.0
9.1
-9.7
24.1
133.6
133.6
218.4
GLY-151
GLY-152
8.3
8.5
-4.9
17.0
95.6
91.3
-126.6
GLY-152
THR-153
4.8
5.1
-17.2
2.6
152.6
148.5
-318.0
THR-153
CYS-154
3.6
3.4
0.7
17.5
30.0
36.9
293.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLY-169
LEU-170
3.3
3.2
8.1
-2.5
48.0
49.1
100.3
LEU-170
LEU-171
6.7
6.7
4.9
-4.4
40.6
38.9
-23.1
LEU-171
SER-172
6.4
6.4
2.0
5.3
45.3
41.4
182.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLU-176
ASP-177
4.7
5.5
-3.7
13.0
59.4
64.4
-162.5
ASP-177
ALA-178
8.4
9.3
-14.1
12.0
54.9
56.7
-14.6
ALA-178
GLN-179
9.2
10.0
0.6
-11.4
172.8
168.3
180.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-184
LEU-185
8.6
9.9
36.6
-47.6
130.0
129.9
344.3
LEU-185
ASP-186
6.6
7.0
35.7
-168.1
86.8
76.9
-2642.9
ASP-186
LYS-187
3.7
5.5
-104.5
-21.2
20.0
36.0
2740.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-191
HIS-192
7.2
6.5
16.1
-13.7
31.4
30.4
73.3
HIS-192
ASP-193
6.5
6.1
8.8
-8.4
53.1
53.6
86.3
ASP-193
TRP-194
9.3
8.8
1.1
-0.5
20.4
19.3
-36.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-195
THR-196
10.9
10.8
8.7
-2.7
87.9
86.5
-63.5
THR-196
MET-197
11.2
11.1
-3.2
0.2
64.3
62.5
-6.6
MET-197
VAL-198
7.9
7.9
-3.2
9.9
4.3
3.6
-138.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLN-202
SER-203
9.7
9.7
5.9
-11.7
77.1
77.3
-61.0
SER-203
HIS-204
13.1
13.2
12.4
-6.8
66.4
71.9
114.4
HIS-204
ILE-205
12.3
12.5
5.2
-9.1
23.8
24.2
-91.6
ILE-205
GLY-206
10.0
10.1
10.6
-2.4
134.8
132.6
-188.1
ILE-205
GLY-206
10.0
10.1
10.6
-2.4
134.8
132.6
-188.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-205
GLY-206
10.0
10.1
10.6
-2.4
134.8
132.6
-188.1
ILE-205
GLY-206
10.0
10.1
10.6
-2.4
134.8
132.6
-188.1
GLY-206
SER-207
12.7
13.0
-1.3
-7.0
77.9
74.0
230.4
SER-207
LEU-208
15.1
15.5
4.9
-1.0
125.6
128.2
-139.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLU-259
ARG-260
6.7
6.5
-1.5
-3.9
54.8
57.0
11.4
ARG-260
PRO-261
6.2
6.2
2.1
2.7
122.9
120.2
73.7
PRO-261
LYS-262
8.6
8.8
1.2
3.5
66.2
63.1
-7.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-274
THR-275
11.4
11.4
-3.3
3.2
84.0
83.1
16.9
THR-275
SER-276
8.7
8.6
2.1
0.4
66.8
63.7
35.1
SER-276
ASP-277
5.3
5.2
-0.4
-3.0
59.5
62.3
-25.2
ASP-277
ASP-278
4.3
4.3
2.6
-2.6
64.2
64.0
50.5
ASP-278
LEU-279
6.8
6.9
-2.3
-3.5
159.5
162.2
-277.7
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLY-333
ASP-334
18.0
17.7
1.7
6.3
13.1
11.8
211.4
ASP-334
TYR-335
19.3
19.0
-9.5
6.1
121.6
121.8
-129.5
TYR-335
MET-336
16.2
15.9
0.3
1.1
94.8
95.4
24.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLU-337
ASN-338
16.2
16.1
5.7
-4.4
167.4
169.5
-9.9
ASN-338
HIS-339
15.6
15.4
-2.2
3.3
79.0
78.7
-58.3
HIS-339
GLY-340
11.8
11.7
0.5
2.7
63.2
63.8
18.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PRO-395
GLN-396
9.2
9.1
-12.7
12.8
57.3
54.8
-135.3
GLN-396
LEU-397
8.3
8.0
7.6
-7.7
155.0
154.4
8.7
LEU-397
SER-398
7.8
7.7
-13.4
-0.6
36.9
35.2
250.9
SER-398
LYS-399
9.4
9.1
9.9
-9.0
115.3
102.0
-168.1
LYS-399
LEU-400
6.6
6.5
-10.7
-11.7
59.2
68.2
244.9
LEU-400
ASN-401
4.6
3.8
-11.6
161.3
19.1
28.0
-3451.2
ASN-401
CYS-402
6.7
6.1
78.4
-9.8
98.8
130.4
5279.5
CYS-402
GLU-403
8.8
7.1
-165.4
5.1
44.9
79.2
-2135.9
GLU-403
ALA-404
11.9
10.8
13.7
-3.9
169.4
147.5
-269.1
ALA-404
VAL-405
10.4
9.9
0.6
20.8
109.9
88.6
90.5
VAL-405
GLY-406
9.0
8.9
-22.4
-14.8
91.2
94.2
83.0
GLY-406
VAL-407
12.7
12.6
8.1
5.2
31.8
33.9
128.2
VAL-407
LYS-408
13.0
12.7
-9.4
4.6
115.1
119.2
68.7
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLN-422
THR-423
18.2
18.0
-1.0
3.2
98.2
97.3
114.7
THR-423
THR-424
16.2
15.8
-3.1
4.2
148.8
149.5
-39.2
THR-424
VAL-425
17.2
16.8
-12.9
11.5
140.4
139.6
-15.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-426
ASN-427
17.0
16.6
-3.4
6.6
115.8
115.2
63.2
ASN-427
ILE-428
15.1
14.8
-3.8
0.0
143.3
145.0
-40.6
ILE-428
TYR-429
13.0
12.7
-2.6
-0.1
140.0
141.1
-24.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-433
ILE-434
11.2
11.2
5.8
-4.3
38.2
38.8
-18.9
ILE-434
ASN-435
11.2
11.2
1.2
1.5
64.8
63.9
41.6
ASN-435
ALA-436
14.6
14.6
6.9
-1.5
116.9
114.5
-65.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-445
ILE-446
14.3
14.3
14.3
-9.8
104.6
101.0
-63.6
ILE-446
HIS-447
16.0
16.2
-2.1
-1.1
71.0
64.9
42.1
HIS-447
ALA-448
19.4
19.6
2.7
11.4
161.0
162.4
-307.2
ALA-448
GLY-449
18.8
18.3
-14.4
-3.4
47.9
52.6
285.9
GLY-449
ARG-450
16.8
16.6
-3.9
11.4
75.7
80.2
-25.1
ARG-450
TYR-451
20.1
19.8
-11.5
3.5
58.5
54.3
117.3
TYR-451
LEU-452
22.4
22.2
2.7
2.6
166.2
164.7
-86.9
LEU-452
ALA-453
20.4
20.1
0.4
-5.6
57.9
61.1
-45.6
LEU-452
ALA-453
20.4
20.1
0.4
-5.6
57.9
61.1
-45.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-452
ALA-453
20.4
20.1
0.4
-5.6
57.9
61.1
-45.6
LEU-452
ALA-453
20.4
20.1
0.4
-5.6
57.9
61.1
-45.6
ALA-453
ARG-454
20.2
20.1
3.3
0.9
74.8
78.6
37.9
ARG-454
ARG-455
24.0
23.9
-1.8
-4.1
137.5
141.0
-60.2
ARG-455
LEU-456
24.3
24.2
3.2
-2.9
30.7
30.0
-21.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-463
THR-464
25.9
25.7
6.2
-10.8
163.0
164.2
82.6
THR-464
ASP-465
23.8
23.6
-5.2
7.5
69.9
70.8
-101.1
ASP-465
TYR-466
25.7
25.3
6.2
-10.2
128.1
123.5
-42.5
TYR-466
SER-467
23.3
23.2
-5.0
0.7
39.9
46.6
109.9
SER-467
ASN-468
26.0
26.0
1.3
-4.1
149.7
155.1
52.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
HIS-502
SER-503
31.2
31.3
-8.3
8.4
164.3
165.5
19.9
SER-503
HIS-504
29.4
29.5
-3.7
-0.7
98.1
98.9
91.5
HIS-504
PHE-505
26.2
26.3
-9.1
-2.9
111.4
115.2
-87.7
PHE-505
LYS-506
24.5
24.5
10.9
-10.6
65.9
72.7
-46.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-513
HIS-514
12.5
12.7
-7.6
3.6
98.8
102.1
-4.8
HIS-514
ARG-515
14.0
13.7
-0.6
1.1
36.2
42.1
-30.9
ARG-515
GLU-516
14.6
14.2
-17.4
1.0
84.0
87.7
60.9
GLU-516
ASP-517
17.6
17.1
-1.8
12.5
87.8
73.3
201.8
ASP-517
ASN-518
21.1
20.6
9.5
-3.9
44.4
39.3
28.2
ASP-517
ASN-518
21.1
20.6
9.5
-3.9
44.4
39.3
28.2
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-517
ASN-518
21.1
20.6
9.5
-3.9
44.4
39.3
28.2
ASP-517
ASN-518
21.1
20.6
9.5
-3.9
44.4
39.3
28.2
ASN-518
VAL-519
23.3
22.9
1.8
10.5
48.0
45.9
359.5
VAL-519
CYS-520
20.6
20.2
8.5
-15.5
40.1
32.2
-163.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees