Adenylate Cyclase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-108   LEU-109  4.7 4.7 -5.1 6.3 91.2 90.5 -19.7
 LEU-109   ASP-110  7.2 7.3 6.3 -2.4 51.2 50.9 54.1
 ASP-110   GLU-111  7.5 7.7 11.4 5.7 77.7 76.1 106.6
 GLU-111   GLU-112  10.6 10.7 -13.4 -3.7 104.1 90.9 7.7
 GLU-112   LYS-113  12.0 12.6 -6.1 18.6 33.4 28.0 -147.5
 LYS-113   GLN-114  12.5 12.8 -4.9 -3.8 52.0 55.9 124.9
 GLN-114   GLU-115  12.8 12.8 1.1 7.4 154.0 153.4 -123.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-260   ALA-261  11.8 11.6 -2.6 1.8 111.1 113.5 -19.8
 ALA-261   VAL-262  13.7 13.4 -1.7 3.0 169.2 170.3 21.4
 VAL-262   LYS-263  12.1 11.7 -2.0 3.2 120.0 118.2 34.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees