Hypoxanthine-Guanine Phosphoribosyltransferase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-60   ILE-61  13.3 14.2 -23.3 30.7 146.8 151.5 39.7
 ILE-61   VAL-62  11.4 11.7 -17.2 -1.3 78.1 85.5 25.9
 VAL-62   ALA-63  11.4 12.0 -5.7 -2.0 136.2 136.6 -37.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-73   PHE-74  5.5 5.8 -7.2 7.6 131.8 125.9 -7.9
 PHE-74   ALA-75  4.9 5.3 0.3 -1.7 26.5 26.9 -13.4
 ALA-75   ASP-76  5.6 5.6 -0.8 3.8 91.8 92.1 12.4
 ASP-76   LEU-77  4.9 4.7 -0.5 -0.6 84.7 83.2 8.8
 LEU-77   LEU-78  1.6 1.2 -5.1 5.0 148.8 145.7 -3.8
 LEU-78   ASP-79  0.5 1.4 -6.3 7.2 134.9 139.6 13.3
 ASP-79   TYR-80  2.9 2.0 -8.1 5.6 84.4 85.7 -12.4
 TYR-80   ILE-81  4.9 4.0 -2.4 3.5 104.9 99.0 -5.3
 ILE-81   LYS-82  4.4 4.1 -5.1 0.7 175.4 169.7 -30.3
 LYS-82   ALA-83  3.4 3.3 3.2 -6.5 70.3 62.6 11.7
 ALA-83   LEU-84  6.5 5.4 17.9 -19.1 90.7 96.5 3.9
 LEU-84   ASN-85  8.7 8.1 9.0 -5.0 42.6 56.8 7.9
 ASN-85   ARG-86  7.8 7.9 0.4 39.3 20.2 18.1 206.6
 ARG-86   ASN-87  7.7 7.5 -35.1 43.7 95.5 105.3 -20.1
 ASN-87   SER-88  11.2 11.2 -26.1 107.0 73.1 91.8 -100.5
 SER-88   ASP-89  13.2 12.7 -15.7 -7.0 104.0 155.2 -90.1
 ASP-89   ARG-90  14.6 15.3 -17.7 -34.5 43.9 110.5 89.8
 ARG-90   SER-91  13.5 15.1 35.1 54.3 78.9 107.4 -40.5
 SER-91   ILE-92  10.9 12.3 7.6 -20.5 125.2 139.7 38.6
 ILE-92   PRO-93  9.7 12.5 32.5 -0.1 58.4 98.6 12.2
 PRO-93   MET-94  9.4 11.7 32.5 -17.2 130.2 159.2 -85.4
 MET-94   THR-95  8.5 10.1 -12.1 0.6 112.6 89.3 -26.8
 THR-95   VAL-96  10.0 11.2 -28.5 8.1 36.2 45.9 44.5
 VAL-96   ASP-97  10.0 9.8 -22.1 -3.8 75.9 79.2 10.6
 ASP-97   PHE-98  12.8 12.5 -31.7 35.3 47.5 35.3 -13.1
 PHE-98   ILE-99  13.6 12.9 -27.0 30.3 51.0 63.7 -82.9
 ILE-99   ARG-100  15.6 15.4 25.4 -16.7 129.2 143.1 -62.3
 ARG-100   LEU-101  16.9 17.3 -0.8 38.9 27.5 49.5 -205.9
 LEU-101   LYS-102  17.1 18.0 18.1 -0.3 118.4 115.0 -75.1
 ILE-113   LYS-114  20.3 21.5 20.0 -14.7 40.0 21.1 16.3
 LYS-114   VAL-115  22.2 22.6 3.8 -10.3 37.2 51.7 -29.9
 VAL-115   ILE-116  21.0 20.3 57.3 -27.8 37.3 33.7 136.5
 ILE-116   GLY-117  22.1 21.1 -139.3 -58.8 157.2 143.6 871.7
 GLY-117   GLY-118  21.7 18.4 86.7 69.0 92.6 30.0 -919.5
 GLY-118   ASP-119  20.6 19.2 -59.8 -27.7 91.9 108.5 359.0
 ASP-119   ASP-120  23.4 19.8 172.4 12.9 47.5 138.7 186.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-177   VAL-178  5.2 5.7 -14.9 11.4 62.6 66.3 6.6
 VAL-178   GLY-179  2.7 3.2 -2.0 9.3 104.5 107.0 6.9
 GLY-179   PHE-180  4.0 4.0 -8.1 0.3 36.1 39.1 32.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees