Hyaluronidase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-213   ILE-214  4.5 4.6 2.9 -4.8 124.3 124.4 15.5
 ILE-214   TYR-215  6.5 6.5 18.7 -3.2 76.4 81.2 41.0
 TYR-215   ALA-216  9.9 10.2 -3.5 7.9 39.5 26.7 -115.1
 ALA-216   PRO-217  12.4 12.1 -15.6 15.3 86.3 81.4 15.6
 PRO-217   LYS-218  15.3 15.3 -22.6 2.1 59.8 44.9 162.7
 LYS-218   ASP-219  18.4 17.4 -2.8 -14.9 123.2 109.3 -114.2
 ASP-219   ASP-220  20.7 20.5 3.3 34.2 65.4 40.1 272.0
 ASP-220   PRO-221  19.4 19.9 12.6 8.9 138.2 129.0 -221.3
 PRO-221   TYR-222  21.6 22.5 -13.4 -5.6 83.3 81.4 16.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-228   GLU-229  22.8 23.6 4.0 9.7 165.3 157.9 -117.9
 GLU-229   PRO-230  24.0 25.0 2.1 -15.1 137.0 140.6 96.7
 PRO-230   TYR-231  22.6 23.9 0.6 -3.5 124.0 130.4 -81.9
 TYR-231   PRO-232  21.7 22.4 -1.8 13.8 52.0 40.8 -153.2
 PRO-232   GLU-233  24.8 24.8 -11.4 -2.1 24.7 38.0 73.0
 GLU-233   SER-234  24.5 24.1 -14.9 9.0 72.2 64.8 -0.5
 SER-234   GLU-235  24.5 22.7 -14.9 33.3 103.8 120.9 59.9
 GLU-235   MET-236  21.3 20.3 -17.2 -12.2 76.0 92.8 200.1
 MET-236   GLN-237  19.4 19.1 7.0 -0.2 130.8 148.1 26.5
 GLN-237   ARG-238  17.8 18.2 9.7 -10.9 67.1 86.9 -123.9
 ARG-238   MET-239  16.5 16.2 13.5 -2.3 55.2 56.1 180.3
 MET-239   GLN-240  14.8 14.3 -1.1 10.0 58.7 53.5 -54.9
 GLN-240   GLU-241  13.7 13.7 -14.0 9.9 63.8 59.3 26.3
 GLU-241   LEU-242  11.6 11.8 9.1 -14.2 49.5 54.0 70.8
 LEU-242   ILE-243  10.0 9.9 7.5 -6.8 80.6 77.5 -67.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-253   VAL-254  5.9 5.9 11.9 -7.3 151.0 149.4 -37.0
 VAL-254   PHE-255  6.7 6.9 -7.8 9.7 79.2 81.3 28.2
 PHE-255   GLY-256  10.3 10.6 -9.0 -2.5 12.6 11.1 157.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-289   ARG-290  11.7 11.7 -2.7 2.7 121.3 123.5 9.5
 ARG-290   SER-291  10.9 11.1 4.6 -1.0 33.1 34.8 31.3
 SER-291   PHE-292  8.6 8.7 -7.2 4.7 118.0 118.3 40.4
 PHE-292   ALA-293  9.8 9.8 3.8 -8.4 33.2 34.7 -55.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-333   GLU-334  9.8 10.0 4.5 6.5 70.3 65.7 82.7
 GLU-334   TYR-335  7.7 7.8 -0.5 2.5 46.8 45.2 -48.0
 TYR-335   ASP-336  6.5 6.7 -6.3 -0.5 86.9 87.9 65.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-339   MET-340  9.1 9.3 -9.3 5.1 74.9 69.2 -41.9
 MET-340   VAL-341  5.2 5.6 -5.2 3.3 31.6 31.2 27.1
 VAL-341   SER-342  5.4 5.8 -1.5 -2.8 40.6 44.9 8.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-362   VAL-363  4.8 4.7 -5.5 9.4 122.2 119.9 -28.8
 VAL-363   MET-364  2.4 2.4 6.3 -12.7 100.0 105.6 -5.9
 MET-364   TRP-365  2.2 2.1 13.4 -9.2 35.5 37.6 83.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-387   ASN-388  5.2 5.0 3.5 -38.6 74.0 73.9 -321.0
 ASN-388   ARG-389  8.9 8.6 22.9 18.4 11.9 21.9 572.7
 ARG-389   ASN-390  8.7 8.1 -13.0 0.4 118.9 116.8 -151.6
 ASN-390   MET-391  7.9 7.6 2.2 2.4 96.8 99.4 -25.4
 ASN-390   MET-391  7.9 7.6 2.2 2.4 96.8 99.4 -25.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-390   MET-391  7.9 7.6 2.2 2.4 96.8 99.4 -25.4
 ASN-390   MET-391  7.9 7.6 2.2 2.4 96.8 99.4 -25.4
 MET-391   ALA-392  4.4 4.3 -9.2 5.2 22.6 23.2 70.1
 ALA-392   VAL-393  2.4 2.5 12.3 -7.7 76.4 72.9 53.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees