Beta 2 Adrenergic Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-224   GLU-225  3.2 4.8 -15.1 2.4 133.9 148.9 -16.5
 GLU-225   ALA-226  2.2 3.6 17.7 -6.3 85.3 76.3 15.9
 ALA-226   LYS-227  2.2 0.4 2.3 -63.7 59.2 60.4 -56.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-282   THR-283  3.2 2.6 4.8 5.4 60.7 64.2 9.1
 THR-283   LEU-284  3.2 3.5 -6.6 24.8 143.7 145.2 43.7
 LEU-284   CYS-285  2.2 2.8 -2.7 52.8 137.4 147.7 68.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees