Hiv-1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-86   PHE-87  27.3 27.5 7.3 -11.3 95.3 92.0 0.5
 PHE-87   TRP-88  24.0 24.0 5.5 -7.9 141.5 139.3 146.6
 TRP-88   GLU-89  21.5 22.2 41.1 0.7 146.2 147.5 -396.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-101   LYS-102  7.7 8.1 2.3 9.2 70.9 72.2 91.2
 LYS-102   LYS-103  9.1 9.1 -10.1 0.5 72.2 62.7 54.7
 LYS-103   LYS-104  10.1 10.6 -34.3 25.7 127.0 121.5 -85.2
 LYS-104   SER-105  12.6 12.8 16.9 -12.0 110.5 109.3 34.8
 SER-105   VAL-106  15.3 15.5 8.0 -14.1 139.7 127.1 74.0
 VAL-106   THR-107  16.2 16.1 13.5 -23.8 111.6 112.6 60.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-217   ASP-218  29.0 28.9 0.2 -34.4 132.4 134.1 373.8
 HIS-221   GLN-222  32.0 32.1 -91.4 46.3 87.2 71.0 -17.2
 GLN-222   LYS-223  28.5 28.8 76.4 -73.9 125.5 138.4 -79.3
 LYS-223   GLU-224  27.2 26.6 -11.1 6.7 45.3 50.1 28.6
 GLU-224   PRO-225  25.5 25.8 -22.6 14.7 64.0 44.2 73.8
 PRO-225   PRO-226  23.4 23.4 -8.0 -0.3 46.2 42.4 15.4
 PRO-226   PHE-227  23.7 23.4 17.9 -18.1 20.4 29.1 -27.5
 PHE-227   LEU-228  23.2 23.1 6.3 11.0 93.7 102.1 74.1
 LEU-228   TRP-229  25.5 25.0 43.5 -28.7 39.3 63.2 149.3
 TRP-229   MET-230  23.8 24.2 -42.0 29.1 82.1 71.2 99.2
 MET-230   GLY-231  25.2 27.0 -73.4 76.6 19.7 13.5 -85.1
 GLY-231   TYR-232  26.7 27.0 15.9 -0.9 132.9 113.2 -119.9
 TYR-232   GLU-233  23.7 23.5 -15.0 -5.5 81.1 93.4 27.3
 GLU-233   LEU-234  23.2 22.9 -10.2 29.8 82.4 86.2 -54.1
 LEU-234   HIS-235  20.0 19.5 29.6 -25.0 113.6 119.7 -68.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees