Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-204   VAL-205  10.3 10.2 9.0 -13.5 111.7 111.0 -4.3
 VAL-205   PRO-206  6.8 6.5 13.9 -11.6 56.9 52.7 20.1
 PRO-206   SER-207  3.9 3.9 -1.9 6.6 136.2 133.8 23.8
 SER-207   ASP-208  2.0 1.9 11.4 -10.9 106.4 106.8 11.9
 ASP-208   THR-209  1.8 1.9 16.0 6.0 78.0 76.7 11.1
 THR-209   LEU-210  4.0 4.2 -10.5 -1.3 31.3 26.9 25.7
 LEU-210   GLN-211  4.7 4.7 -26.6 12.2 57.4 66.7 35.9
 GLN-211   ALA-212  4.9 4.5 7.5 -6.3 72.6 68.7 6.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-342   GLN-343  3.1 3.6 -9.5 7.9 156.3 152.1 -1.9
 GLN-343   SER-344  2.9 2.9 -21.1 -22.0 87.1 89.4 1.5
 SER-344   PRO-345  6.6 6.5 35.9 1.9 27.9 22.8 109.8
 PRO-345   GLU-346  7.6 7.8 17.9 7.2 82.4 86.6 10.8
 GLU-346   VAL-347  10.7 10.5 7.0 -3.2 85.2 84.9 -10.2
 VAL-347   ARG-348  13.8 13.9 -2.5 -1.4 131.2 132.0 -18.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-472   GLY-473  11.2 10.8 6.5 -6.3 122.2 119.5 0.8
 GLY-473   ASP-474  11.8 11.5 -5.0 0.2 49.0 44.7 8.1
 ASP-474   ALA-475  8.8 8.7 -7.5 -3.1 21.2 26.3 41.8
 ALA-475   PRO-476  8.7 9.1 -5.5 1.8 62.4 58.9 1.3
 PRO-476   GLY-477  8.1 8.2 -8.1 -46.6 68.1 57.6 69.7
 GLY-477   ARG-478  4.7 5.0 36.0 -26.7 158.0 110.7 -28.7
 ARG-478   TYR-479  3.6 2.8 60.8 -7.7 98.7 105.1 -21.2
 TYR-479   ASP-480  1.7 1.7 -0.6 -10.4 29.1 25.8 31.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees