Fibroblast Growth Factor Receptor 3

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-531   ILE-532  13.3 13.8 -32.6 7.9 93.3 97.3 23.5
 ILE-532   GLY-533  9.6 10.0 1.4 -5.1 100.4 115.2 38.8
 GLY-533   LYS-534  10.1 10.9 32.0 -0.9 126.8 125.3 -65.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-538   ILE-539  2.2 2.2 24.9 -15.6 34.1 31.7 46.7
 ILE-539   ASN-540  4.3 4.4 -21.2 -0.4 81.6 72.8 -2.8
 ASN-540   LEU-541  7.2 7.4 28.2 -1.6 73.3 62.1 81.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-556   TYR-557  6.4 6.3 7.6 -8.8 117.5 116.5 31.9
 TYR-557   ALA-558  4.7 4.5 16.8 -16.8 78.0 73.3 15.3
 ALA-558   ALA-559  2.7 2.5 -25.5 10.9 40.5 39.2 79.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-632   ILE-633  1.7 1.2 2.6 -4.6 116.9 114.0 9.8
 ILE-633   ALA-634  3.9 3.3 -3.2 19.5 110.4 107.6 26.4
 ALA-634   ASP-635  6.8 6.2 -24.3 2.5 60.0 47.5 82.4
 ASP-635   PHE-636  10.5 9.5 -45.1 10.2 162.9 171.6 -190.5
 ASP-635   PHE-636  10.5 9.5 -45.1 10.2 162.9 171.6 -190.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-635   PHE-636  10.5 9.5 -45.1 10.2 162.9 171.6 -190.5
 ASP-635   PHE-636  10.5 9.5 -45.1 10.2 162.9 171.6 -190.5
 PHE-636   GLY-637  11.0 8.1 -50.0 -29.5 106.1 110.7 -79.3
 GLY-637   LEU-638  14.7 11.0 29.7 51.5 17.5 85.7 301.5
 LEU-638   ALA-639  14.6 13.8 134.1 -16.7 51.0 27.7 665.4
 LEU-656   PRO-657  20.4 22.1 14.6 -2.1 117.7 93.7 -61.4
 PRO-657   VAL-658  18.7 19.3 -15.8 -0.5 132.1 147.7 -108.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees