Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-206   SER-207  7.9 8.1 17.0 -4.1 43.1 39.6 141.2
 SER-207   ASP-208  6.1 6.2 20.6 -2.5 94.7 88.7 -43.1
 ASP-208   THR-209  2.4 2.6 -24.4 14.2 48.7 38.9 -23.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-233   GLY-234  7.8 8.1 -6.7 10.1 84.9 71.9 -14.7
 GLY-234   ASN-235  5.2 5.7 25.7 -8.8 30.3 39.8 206.7
 ASN-235   TYR-236  4.9 4.7 -2.1 -2.3 143.2 149.8 -61.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-240   MET-241  4.5 4.4 -10.5 14.6 63.7 68.5 -4.8
 MET-241   ASP-242  7.9 7.8 -8.1 9.0 67.4 69.1 -16.0
 ASP-242   ALA-243  9.9 9.7 7.2 -19.5 156.3 158.7 130.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-341   LEU-342  10.1 10.7 17.1 -19.6 65.1 69.8 -3.3
 LEU-342   GLN-343  9.9 10.4 -23.0 18.2 107.6 110.2 -47.2
 GLN-343   SER-344  13.1 13.1 -29.5 -23.3 54.2 59.9 452.2
 SER-344   PRO-345  16.1 16.0 18.5 -4.3 66.5 90.1 -44.3
 PRO-345   GLU-346  19.0 19.4 30.9 -8.5 129.2 138.3 -238.0
 GLU-346   VAL-347  22.3 22.1 16.6 21.9 70.9 66.9 162.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-474   ALA-475  12.4 12.4 14.4 -7.8 133.9 135.2 -68.7
 ALA-475   PRO-476  11.6 11.7 3.7 3.4 121.6 123.6 -50.7
 PRO-476   GLY-477  9.5 9.8 -9.4 49.2 123.7 110.1 120.4
 GLY-477   ARG-478  7.5 7.0 -2.9 -22.3 58.1 71.5 142.5
 ARG-478   TYR-479  9.1 9.1 -55.6 38.0 131.4 119.5 -135.7
 TYR-479   ASP-480  8.9 8.2 -10.0 -9.3 64.9 61.8 155.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees