Streptokinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-161   TYR-162  6.0 5.9 3.1 -1.3 48.0 48.9 26.2
 TYR-162   THR-163  5.8 5.3 7.6 -0.8 27.7 29.9 38.3
 THR-163   VAL-164  4.2 3.5 1.2 -8.1 53.8 56.7 -12.2
 VAL-164   GLN-165  4.2 3.6 -12.9 19.6 29.8 25.0 -19.4
 VAL-164   GLN-165  4.2 3.6 -12.9 19.6 29.8 25.0 -19.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-164   GLN-165  4.2 3.6 -12.9 19.6 29.8 25.0 -19.4
 VAL-164   GLN-165  4.2 3.6 -12.9 19.6 29.8 25.0 -19.4
 GLN-165   PHE-166  2.5 2.1 -8.2 6.8 53.3 52.7 -4.0
 PHE-166   THR-167  4.5 4.4 -5.9 5.3 38.7 37.0 24.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-170   PRO-171  8.0 7.7 14.1 -18.8 88.1 92.1 -41.4
 PRO-171   ASP-172  4.5 4.1 18.2 -21.7 79.1 87.0 -4.8
 ASP-172   ASP-173  2.4 3.1 -16.3 9.2 71.7 65.0 39.3
 ASP-173   ASP-174  2.6 3.2 24.6 -21.5 133.7 137.3 0.5
 ASP-174   PHE-175  5.5 5.8 10.4 -12.9 160.1 153.2 12.7
 PHE-175   ARG-176  3.2 3.1 -13.0 5.0 80.7 83.7 29.9
 ARG-176   PRO-177  5.1 4.6 1.0 5.0 152.4 151.5 -33.7
 PRO-177   GLY-178  4.8 4.4 2.9 0.6 125.2 123.5 -1.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-182   LYS-183  7.8 7.0 47.2 -23.0 62.7 80.4 45.9
 LYS-183   LEU-184  10.1 9.3 -19.9 7.8 155.9 157.4 -64.9
 LEU-184   LEU-185  10.5 10.2 4.8 -5.4 91.9 93.2 16.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-225   HIS-226  3.7 3.7 -0.6 5.9 36.7 39.0 -46.3
 HIS-226   ASP-227  2.9 2.9 -16.7 29.7 72.8 76.5 7.8
 ASP-227   ASN-228  4.9 4.9 154.5 -159.4 82.0 59.8 62.5
 ASN-228   ASP-229  8.1 8.2 9.7 12.0 107.2 105.8 -13.8
 ASP-229   ILE-230  8.5 8.4 0.9 -12.8 30.8 32.2 -35.6
 ILE-230   PHE-231  11.0 10.9 2.7 2.3 72.7 82.3 14.9
 PHE-231   ARG-232  10.5 10.5 3.1 -12.5 72.4 71.5 16.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-244   VAL-245  10.3 10.2 -3.5 -3.9 80.7 79.7 22.6
 VAL-245   LYS-246  6.7 6.8 -4.7 -0.3 48.1 40.6 20.9
 LYS-246   ASN-247  5.8 5.6 2.4 2.4 146.5 142.9 -12.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-269   ILE-270  1.5 1.1 5.3 -3.9 119.2 112.7 -9.1
 ILE-270   SER-271  3.2 3.0 10.0 -16.4 166.9 167.0 60.2
 SER-271   GLU-272  2.2 2.4 7.7 -4.0 120.8 118.9 -36.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees