Hepatocyte Growth Factor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-119   GLU-120  7.3 7.1 -15.8 14.2 78.7 76.0 3.5
 GLU-120   ASN-121  4.3 4.2 3.9 -13.9 121.9 121.1 30.0
 ASN-121   LYS-122  1.8 1.6 3.6 -4.6 56.3 56.1 16.3
 LYS-122   ASP-123  1.8 2.0 7.6 0.3 97.0 105.1 2.1
 ASP-123   TYR-124  4.5 4.6 13.4 -27.7 55.8 63.9 -16.7
 TYR-124   ILE-125  5.6 5.9 -5.9 14.8 168.5 172.5 19.7
 ILE-125   ARG-126  4.4 4.7 -13.3 14.9 96.3 104.3 28.2
 ARG-126   ASN-127  7.4 7.9 4.4 -14.8 84.6 75.6 3.0
 ASN-127   CYS-128  8.2 8.6 3.6 4.5 59.4 61.2 22.3
 CYS-128   ILE-129  11.2 11.5 -0.3 -21.0 161.3 153.1 -95.1
 ILE-129   ILE-130  11.5 11.6 15.7 7.5 67.4 68.9 32.7
 ILE-130   GLY-131  12.6 13.7 -4.1 0.4 165.3 156.8 -15.1
 GLY-131   LYS-132  14.1 14.9 21.3 -13.7 76.2 74.9 18.0
 LYS-132   GLY-133  12.2 12.3 -5.8 4.8 50.5 58.0 17.9

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees