Mitogen-Activated Protein Kinase 8

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-80   ASN-81  2.8 2.8 8.7 14.5 42.1 38.1 112.3
 ASN-81   HIS-82  5.9 5.8 -15.6 13.9 95.1 89.5 17.7
 HIS-82   LYS-83  8.6 8.1 -14.6 9.4 171.3 159.0 -23.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-85   ILE-86  7.2 6.8 -0.6 -14.6 53.2 49.0 39.2
 ILE-86   GLY-87  4.3 4.3 17.1 -2.6 66.5 65.8 22.0
 GLY-87   LEU-88  3.1 1.9 10.5 -13.2 106.3 108.0 5.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-108   GLU-109  1.7 1.7 -16.0 12.1 137.7 135.6 -1.2
 GLU-109   LEU-110  2.0 1.7 -7.7 24.5 126.1 124.2 79.9
 LEU-110   MET-111  2.5 2.6 -6.5 2.1 103.8 91.9 14.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-333   PRO-334  11.7 11.0 12.4 -26.4 102.8 107.1 6.5
 PRO-334   PRO-335  8.0 7.4 -1.3 12.5 68.7 85.1 -2.4
 PRO-335   LYS-336  5.2 4.6 -154.3 91.6 130.0 149.3 -254.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees