Haematopoetic Cell Kinase (Hck)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-150   LYS-151  9.2 9.2 5.8 0.3 88.1 88.4 -9.0
 LYS-151   GLY-152  9.3 8.8 2.8 4.1 130.5 126.4 -31.2
 GLY-152   ILE-153  7.2 6.5 -1.5 1.0 68.3 72.4 36.5
 ILE-153   SER-154  3.9 3.4 -8.7 -0.6 124.8 126.8 -48.3
 SER-154   ARG-155  1.3 0.6 1.6 0.3 69.2 71.9 51.4
 ARG-155   LYS-156  2.3 3.1 7.8 -14.8 137.3 135.5 -15.5
 LYS-156   ASP-157  4.5 5.2 4.3 3.6 124.6 127.9 -0.6
 ASP-157   ALA-158  2.9 3.6 -0.7 -4.5 121.4 118.8 -13.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-316   LEU-317  14.5 15.7 -7.7 -8.9 127.1 126.1 -56.1
 LEU-317   GLN-318  11.8 13.1 -19.3 19.1 100.5 94.1 -21.7
 GLN-318   HIS-319  9.6 10.3 20.5 0.6 33.7 35.9 140.2
 HIS-319   ASP-320  6.7 7.4 -3.7 1.0 76.4 81.4 15.1
 ASP-320   LYS-321  3.1 4.0 5.9 -8.9 122.9 119.4 -23.2
 LYS-321   LEU-322  3.2 3.4 -6.7 9.2 28.6 24.5 6.8
 LEU-322   VAL-323  4.8 4.9 1.7 18.6 122.6 116.7 -95.4
 VAL-323   LYS-324  3.4 3.3 -6.4 8.0 84.3 89.2 -0.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-336   ILE-337  8.4 9.0 20.7 -19.1 66.8 69.1 25.1
 ILE-337   THR-338  8.1 8.6 -4.1 7.6 166.5 164.6 20.8
 THR-338   GLU-339  6.2 6.6 -4.8 12.6 106.3 104.3 -25.3
 GLU-339   PHE-340  6.0 6.5 -1.3 2.4 66.1 60.5 19.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-401   ILE-402  2.7 2.8 31.1 -13.4 49.3 46.6 96.4
 ILE-402   ALA-403  5.8 5.7 -0.3 18.2 138.5 138.9 94.9
 ALA-403   ASP-404  5.6 5.2 0.7 -8.0 57.8 65.1 -48.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-409   VAL-410  18.1 17.0 -3.3 21.9 36.0 29.4 -159.5
 VAL-410   ILE-411  17.3 15.4 -56.8 -38.7 30.4 41.9 660.9
 PRO-425   ILE-426  18.4 18.6 115.2 -79.1 63.0 67.9 133.8
 ILE-426   LYS-427  22.2 22.0 14.3 -4.9 36.7 31.6 88.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees