Thymidylate Synthase
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLN-3
PHE-4
4.6
4.1
33.2
124.6
133.7
126.3
-1051.5
PHE-4
ASP-5
1.2
1.9
35.2
-30.7
105.3
99.0
-86.6
ASP-5
LYS-6
3.7
3.9
-3.0
2.3
50.6
52.0
-20.5
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLN-7
TYR-8
4.1
4.8
-2.8
7.6
117.3
117.9
47.6
TYR-8
ASN-9
2.9
3.1
4.2
-1.3
69.0
64.0
21.8
ASN-9
SER-10
6.7
6.9
5.7
-1.2
33.8
34.0
36.9
SER-10
ILE-11
7.1
7.1
-5.4
8.5
148.3
145.7
45.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-41
SER-42
9.8
9.3
12.1
6.2
73.1
76.6
96.3
SER-42
VAL-43
6.1
5.5
5.5
-17.7
106.9
92.1
12.1
VAL-43
ILE-44
2.6
2.2
-23.3
19.6
91.7
87.5
35.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-45
LYS-46
4.4
4.5
7.7
-5.1
140.3
141.9
-6.6
LYS-46
GLN-47
3.5
3.8
1.5
-11.8
135.1
135.0
36.5
GLN-47
MET-48
5.8
5.9
4.3
-9.3
154.4
152.1
40.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ARG-49
PHE-50
8.4
8.9
-5.0
15.0
168.3
158.9
153.0
PHE-50
ASP-51
8.7
9.2
15.1
-8.9
65.7
64.1
-2.2
ASP-51
ASN-52
11.7
12.0
8.3
-2.8
40.7
36.6
52.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-180
ARG-181
10.3
10.3
14.9
0.0
17.1
23.1
141.5
ARG-181
SER-182
10.5
10.1
-4.6
-11.8
95.8
93.6
25.6
SER-182
ASN-183
9.7
8.8
25.0
-31.8
161.9
159.6
47.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-184
MET-185
10.0
9.5
10.4
-5.8
36.2
36.2
60.1
MET-185
ALA-186
7.6
7.1
1.9
-3.0
39.0
40.1
-0.4
ALA-186
LEU-187
10.5
10.2
2.4
-0.9
55.5
61.2
7.0
LEU-187
GLY-188
12.4
12.2
30.1
-32.8
99.2
100.2
-23.0
LEU-187
GLY-188
12.4
12.2
30.1
-32.8
99.2
100.2
-23.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-187
GLY-188
12.4
12.2
30.1
-32.8
99.2
100.2
-23.0
LEU-187
GLY-188
12.4
12.2
30.1
-32.8
99.2
100.2
-23.0
GLY-188
ASN-189
11.5
10.6
-25.2
32.0
68.6
64.9
-9.0
ASN-189
PRO-190
7.8
7.0
-2.1
-9.2
7.9
15.0
70.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASN-192
VAL-193
10.3
10.0
16.0
-6.8
63.4
70.9
12.4
VAL-193
PHE-194
7.5
7.4
-15.0
23.1
160.4
155.1
55.2
PHE-194
GLN-195
8.5
8.3
-4.2
10.5
96.2
89.2
-25.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
CYS-221
HIS-222
4.2
3.8
-18.6
21.5
101.9
103.8
-13.0
HIS-222
VAL-223
7.1
7.0
-1.8
-13.5
39.8
40.2
110.7
VAL-223
TYR-224
9.9
9.9
22.1
-13.9
60.8
64.9
92.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LYS-232
ILE-233
14.9
15.0
6.7
-0.7
15.6
15.3
62.9
ILE-233
GLN-234
16.1
16.2
1.0
1.8
56.6
54.7
4.9
GLN-234
MET-235
12.7
12.8
-10.2
7.7
89.9
96.7
14.2
MET-235
GLU-236
11.6
11.7
5.1
2.5
56.7
51.9
67.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASN-266
TYR-267
4.3
5.0
26.1
-11.1
19.8
18.5
152.9
TYR-267
LYS-268
5.7
6.2
-0.4
-10.8
91.3
91.1
5.6
LYS-268
HIS-269
7.0
7.3
-20.3
28.0
166.2
159.8
63.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees