Fibroblast Growth Factor Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-247   VAL-248  13.5 13.5 10.3 -20.5 139.0 137.6 52.8
 VAL-248   VAL-249  12.9 13.1 -2.5 2.1 62.3 53.8 16.0
 VAL-249   GLU-250  10.1 10.6 7.5 -2.1 160.7 158.3 -33.8
 GLU-250   ARG-251  9.8 10.4 9.2 -26.7 97.2 100.4 13.6
 ARG-251   SER-252  6.1 6.8 -3.4 -10.5 23.7 14.3 72.1
 SER-252   PRO-253  6.6 6.8 12.6 -7.3 95.8 114.4 -36.8
 PRO-253   HIS-254  6.2 6.1 29.8 -6.6 57.6 57.7 60.6

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees