Pyruvate Kinase Isozymes M1/m2
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LYS-115
GLY-116
5.6
5.6
14.0
-0.2
61.1
66.4
19.4
GLY-116
PRO-117
1.8
1.8
-18.1
-3.0
107.7
94.9
-25.0
PRO-117
GLU-118
2.9
2.9
46.2
-20.1
45.9
31.1
90.2
GLU-118
ILE-119
5.5
5.5
28.9
-10.1
88.4
90.0
20.2
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-217
LEU-218
10.5
10.7
-7.6
23.5
137.3
139.2
43.4
LEU-218
PRO-219
7.5
7.9
16.5
-6.5
70.7
55.5
-0.9
PRO-219
ALA-220
6.0
6.7
2.1
12.6
109.6
108.3
-13.5
ALA-220
VAL-221
4.4
5.5
-9.2
-2.2
131.3
112.4
5.9
VAL-221
SER-222
2.8
2.8
14.5
9.4
58.3
64.8
50.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees