Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  11.2 10.7 9.3 1.4 73.3 72.3 1.1
 ILE-639   ALA-640  7.6 7.2 6.4 6.7 143.6 142.0 -15.2
 ALA-640   ASP-641  5.3 4.9 -24.1 1.7 104.7 104.4 -4.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  13.1 14.5 26.4 51.5 114.0 81.6 -29.2
 LEU-662   PRO-663  10.2 12.7 -25.7 25.1 57.5 93.9 4.8
 PRO-663   VAL-664  8.2 9.3 -95.1 -10.8 14.1 44.9 120.3
 VAL-664   LYS-665  8.9 9.2 17.8 -8.8 130.0 134.5 0.3
 LYS-665   TRP-666  8.0 7.9 6.7 5.0 85.6 78.7 -3.7
 TRP-666   MET-667  4.4 4.6 -1.6 5.0 83.1 84.4 1.3
 MET-667   ALA-668  4.7 4.5 -7.4 19.4 22.7 29.0 -11.5
 ALA-668   PRO-669  4.7 4.3 2.5 -18.1 107.6 111.9 13.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees