Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-114
LYS-115
6.1
6.4
-3.2
8.4
131.0
131.6
12.4
LYS-115
GLY-116
6.6
7.0
-6.1
18.2
103.9
107.1
38.9
GLY-116
PRO-117
3.5
3.7
-29.7
18.3
100.9
92.5
12.4
PRO-117
GLU-118
5.6
5.2
68.6
-53.2
30.8
27.2
68.2
GLU-118
ILE-119
7.6
7.9
7.2
-0.5
91.6
93.5
-7.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-218
PRO-219
9.5
9.4
1.9
6.3
62.4
53.6
25.5
PRO-219
ALA-220
7.2
7.4
22.4
-1.4
110.3
114.6
-25.0
ALA-220
VAL-221
4.5
4.7
15.6
-16.3
59.3
84.3
10.8
VAL-221
SER-222
2.4
2.3
52.7
-18.0
63.8
74.1
86.3
SER-222
GLU-223
5.1
5.3
-6.9
-8.9
152.9
155.5
-54.5
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees