Human Immunodeficiency Virus Type 1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TRP-239   THR-240  6.3 6.7 -11.5 1.3 129.7 128.1 -20.7
 THR-240   VAL-241  7.9 8.1 41.4 -71.0 75.9 63.2 -16.9
 VAL-241   GLN-242  9.0 8.3 -76.1 27.4 163.2 159.4 -132.1
 GLN-242   PRO-243  7.9 8.3 -173.9 -9.9 115.3 129.6 307.6
 PRO-243   ILE-244  10.8 9.0 -80.7 -4.1 95.0 85.5 86.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-314   HIS-315  13.6 15.1 15.9 2.6 76.2 67.7 11.7
 HIS-315   GLY-316  11.6 12.3 -15.8 71.8 158.0 172.9 156.3
 GLY-316   VAL-317  11.4 11.5 -39.4 27.2 109.2 114.2 -19.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees