Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-209   LEU-210  5.6 5.7 -15.2 9.5 18.8 20.8 30.6
 LEU-210   GLN-211  4.3 4.6 -24.8 16.3 53.2 53.5 54.6
 GLN-211   ALA-212  3.9 3.7 1.7 -3.8 105.9 100.4 20.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-339   ILE-340  9.2 9.6 -7.3 -18.5 83.4 92.7 18.4
 ILE-340   LYS-341  6.1 5.9 -24.5 0.3 58.8 32.4 82.0
 LYS-341   LEU-342  6.6 5.8 10.5 13.7 103.0 86.7 -56.2
 LEU-342   GLN-343  6.0 5.2 7.4 7.8 56.0 52.4 17.0
 GLN-343   SER-344  8.1 7.4 -14.5 -21.9 53.2 60.2 65.5
 SER-344   PRO-345  11.7 11.1 92.5 -87.8 57.0 46.7 28.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-474   ALA-475  8.3 7.4 -15.4 39.4 34.3 32.3 -52.5
 ALA-475   PRO-476  8.5 8.0 -15.0 9.9 30.8 50.4 7.4
 PRO-476   GLY-477  8.2 7.7 -11.4 51.3 76.6 65.7 -81.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees