Glutamate Receptor, Ionotropic Kainate 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  MET-106   THR-107  10.1 10.0 1.2 25.9 41.6 49.9 78.2  THR-107   LEU-108  8.3 7.6 25.8 -7.6 112.9 113.9 -84.1  LEU-108   GLY-109  4.8 3.8 -27.9 36.2 135.6 138.2 22.1  GLY-109   ILE-110  2.3 2.1 -49.9 31.4 60.2 66.9 34.8  ILE-110   SER-111  3.6 3.3 -4.8 -6.2 58.6 64.3 29.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-208   GLY-209  11.9 12.0 27.9 -33.4 101.3 95.1 -38.5  GLY-209   LEU-210  10.7 9.8 0.7 12.1 104.8 115.4 -14.5  LEU-210   ILE-211  7.3 6.6 3.1 2.3 155.1 157.5 -6.1  ILE-211   ASP-212  6.4 6.7 -161.6 155.0 68.3 45.2 -55.3  ASP-212   SER-213  3.6 3.9 133.2 -103.1 73.6 62.6 64.6  SER-213   LYS-214  4.7 4.4 -19.0 12.9 77.0 72.9 29.4  LYS-214   GLY-215  4.7 4.8 35.9 -29.9 41.5 36.6 18.8 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  TRP-250   TRP-251  9.3 9.5 -6.5 -3.0 95.9 92.8 9.6  TRP-251   ARG-252  5.9 6.3 3.8 -4.3 147.7 141.4 1.8  ARG-252   GLY-253  6.1 6.7 -14.2 -31.1 53.3 48.8 116.4  GLY-253   ASN-254  3.2 3.7 -10.4 40.1 26.0 58.5 -101.2  ASN-254   GLY-255  3.7 4.8 -59.2 -33.3 71.1 125.9 2.2  GLY-255   CYS-256  5.3 6.1 36.5 5.4 72.3 112.7 -7.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees