Cadherin-23

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-107   PRO-108  3.3 3.0 -5.3 2.5 76.1 76.5 6.3
 PRO-108   THR-109  0.5 0.8 -4.4 2.8 10.6 10.6 -9.1
 THR-109   PHE-110  2.2 2.4 1.3 -13.4 89.4 96.1 71.5
 PHE-110   HIS-111  5.6 5.6 -22.6 8.0 54.0 35.8 169.5
 HIS-111   ASN-112  8.5 7.6 23.1 -7.5 121.5 117.4 -115.1
 ASN-112   GLN-113  11.0 10.2 9.2 -9.2 112.9 101.8 2.9
 GLN-113   PRO-114  9.6 9.3 -1.9 -5.7 16.1 12.9 -45.9
 PRO-114   TYR-115  11.0 11.1 -3.5 9.1 125.0 124.2 56.1
 TYR-115   SER-116  13.7 13.6 0.6 10.2 110.0 103.5 -58.0
 SER-116   VAL-117  17.2 17.3 3.0 -2.0 77.0 71.1 -7.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-132   ASN-133  12.6 12.6 -9.6 8.1 59.4 59.4 -34.9
 ASN-133   ALA-134  10.0 10.0 -4.1 21.6 109.4 116.5 64.1
 ALA-134   THR-135  6.3 6.3 -18.2 34.8 50.8 60.5 -49.6
 THR-135   ASP-136  5.4 5.9 -16.8 9.0 90.8 74.9 66.3
 ASP-136   PRO-137  3.8 4.2 -10.6 -1.1 65.9 69.0 45.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-140   ALA-141  5.8 6.3 -7.3 4.2 73.9 74.2 -15.7
 ALA-141   GLY-142  2.2 2.5 -0.1 -8.1 20.6 18.9 59.3
 GLY-142   GLY-143  3.5 3.5 2.5 1.7 134.7 135.0 -38.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-189   LYS-190  4.8 4.4 4.6 -13.9 123.8 121.0 21.5
 LYS-190   THR-191  7.0 6.4 10.6 -3.8 68.7 73.4 30.6
 THR-191   ARG-192  10.4 9.9 -21.3 20.6 165.3 165.8 -19.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-193   LEU-194  7.0 6.6 -2.5 4.8 10.7 10.4 -23.3
 LEU-194   SER-195  6.3 5.7 0.2 -0.2 108.2 106.9 -1.1
 SER-195   THR-196  5.9 5.6 -7.6 1.4 5.0 7.5 72.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees