Tubulin

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-22   VAL-23  6.0 6.8 8.2 -47.2 54.2 67.6 -10.8
 VAL-23   ILE-24  5.9 6.1 -56.0 39.0 120.1 117.1 -9.0
 ILE-24   SER-25  2.5 3.0 33.1 -36.0 32.4 41.3 9.7
 SER-25   ASP-26  2.8 2.9 -78.2 13.3 120.9 143.9 -36.5
 ASP-26   GLU-27  4.0 5.5 -26.5 -145.0 113.5 112.2 65.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-43   LEU-44  8.7 4.8 149.5 -53.4 45.6 82.1 38.1
 LEU-44   GLU-47  9.3 5.7 36.7 66.4 118.8 100.0 -34.2
 GLU-47   ARG-48  9.0 9.5 143.4 65.4 168.8 21.1 25.2
 ARG-48   ILE-49  9.1 9.7 157.9 68.1 108.2 54.8 -43.9
 ILE-49   ASN-50  11.4 6.8 -123.9 117.5 108.9 128.3 18.1
 ASN-50   VAL-51  13.8 10.0 160.2 7.0 48.3 25.9 109.2
 VAL-51   TYR-52  16.1 8.9 -170.2 -16.1 156.6 121.8 -112.5
 TYR-52   TYR-53  15.7 6.0 170.0 161.9 51.8 109.6 -4.2
 TYR-53   ASN-54  15.5 7.2 26.6 -161.1 90.5 97.0 -45.1
 ASN-54   GLU-55  13.4 10.8 -151.2 -44.2 59.8 28.5 149.0
 GLU-55   ALA-56  13.0 12.7 104.2 -23.4 129.0 93.0 -58.2
 ALA-56   ALA-57  10.4 15.4 -96.8 -96.5 124.1 29.1 40.6
 ALA-57   GLY-58  8.7 15.7 164.6 148.0 102.1 134.0 -108.4
 GLY-58   ASN-59  5.2 13.5 -110.1 84.8 24.5 86.7 8.5
 ASN-59   LYS-60  5.8 11.1 171.5 -96.4 120.6 30.5 23.8
 LYS-60   TYR-61  6.8 11.5 -24.0 -74.3 111.0 133.2 129.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees