Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-112
THR-113
12.5
12.5
0.7
12.1
63.8
61.2
-16.3
THR-113
LYS-114
9.3
9.2
2.2
-13.7
123.6
112.6
17.8
LYS-114
GLY-115
7.5
6.7
-15.7
-13.0
79.4
70.6
26.4
GLY-115
PRO-116
4.2
3.5
17.9
-8.8
82.9
94.9
-2.3
PRO-116
GLU-117
0.6
0.3
-74.5
38.6
33.7
35.8
69.0
GLU-117
ILE-118
3.2
3.2
0.7
-3.0
77.3
79.2
4.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-216
LEU-217
9.4
8.3
68.5
-55.2
129.5
124.5
-11.6
LEU-217
PRO-218
6.0
4.8
-21.6
5.7
61.9
64.1
18.6
PRO-218
ALA-219
5.0
3.9
-7.9
-8.9
124.3
119.1
-6.7
ALA-219
VAL-220
5.8
4.5
6.0
1.9
90.4
118.1
-18.7
VAL-220
SER-221
3.8
3.4
-64.7
51.3
67.5
59.7
-3.8
SER-221
GLU-222
1.8
1.7
-13.3
0.8
32.0
23.6
44.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees