Vitamin D Hydroxylase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-144   ILE-145  12.7 13.2 -0.7 -2.1 82.0 82.2 -33.7
 ILE-145   PRO-146  9.2 9.7 9.6 -0.9 35.4 39.0 29.6
 PRO-146   VAL-147  7.5 8.0 0.3 -7.9 47.5 51.2 -6.1
 VAL-147   GLN-148  9.5 9.4 8.6 -0.3 104.0 112.9 -4.4
 GLN-148   VAL-149  9.6 9.4 -3.6 -2.9 91.8 86.3 22.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-223   GLU-224  7.8 9.5 -19.7 13.2 94.2 88.7 -7.8
 GLU-224   GLU-225  4.4 6.1 -0.5 -10.1 134.7 131.5 -30.0
 GLU-225   LEU-226  3.1 4.8 -2.7 9.8 153.4 162.2 34.9
 LEU-226   VAL-227  5.1 6.4 -5.3 -11.8 104.7 107.1 -76.1
 VAL-227   ALA-228  5.3 5.8 14.6 -0.1 74.7 91.9 30.2
 ALA-228   MET-229  2.3 2.3 -5.8 -1.3 155.3 150.8 -19.7
 MET-229   ALA-230  1.1 1.7 4.5 -5.7 46.0 39.9 -3.2
 ALA-230   MET-231  4.2 3.7 -1.3 1.9 95.6 90.1 21.1
 MET-231   LEU-232  5.3 4.6 8.5 -5.1 58.2 72.3 -4.3
 LEU-232   LEU-233  4.0 3.1 -4.7 15.0 170.5 173.2 84.2
 LEU-233   LEU-234  2.6 2.1 5.0 -8.3 64.9 64.3 -35.0
 LEU-234   ILE-235  6.1 5.5 -4.6 -3.6 96.6 82.9 -22.4
 ILE-235   ALA-236  8.0 7.7 2.6 -20.3 41.7 58.6 -69.6
 ALA-236   GLY-237  6.7 7.3 10.8 -26.7 28.4 6.1 -92.7
 GLY-237   HIS-238  6.3 6.1 8.4 10.7 74.4 60.3 51.0
 HIS-238   GLU-239  10.2 8.8 -54.0 74.9 96.6 100.2 35.7
 GLU-239   THR-240  11.8 12.2 -53.0 58.4 116.4 121.3 33.7
 THR-240   THR-241  11.1 11.9 23.8 -15.3 4.3 8.0 41.6
 THR-241   VAL-242  10.0 10.1 2.0 -9.3 64.1 60.8 4.8
 VAL-242   ASN-243  12.6 12.7 -11.3 17.4 103.2 107.0 14.1
 ASN-243   LEU-244  15.1 15.4 -12.3 11.1 127.5 131.0 -13.0
 LEU-244   ILE-245  13.8 13.9 -0.9 4.5 151.2 150.3 21.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees