Pyruvate Kinase Isozymes M1/m2
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
8.1
8.0
-8.5
1.9
55.5
55.9
12.7
LYS-114
GLY-115
7.3
7.4
5.2
-11.0
103.7
102.7
1.0
GLY-115
PRO-116
3.6
3.6
23.4
-12.4
87.4
93.9
-2.7
PRO-116
GLU-117
4.0
4.0
-55.1
21.5
30.7
36.3
141.3
GLU-117
ILE-118
7.0
6.7
-17.4
16.7
98.2
98.7
-19.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PRO-218
ALA-219
4.9
4.4
-15.6
-2.6
118.2
117.0
-25.6
ALA-219
VAL-220
3.3
2.6
-2.7
7.1
76.7
61.2
8.2
VAL-220
SER-221
0.8
1.0
-21.2
-0.9
61.3
56.2
81.3
SER-221
GLU-222
3.0
2.6
9.4
-6.7
152.3
150.7
-25.7
GLU-222
LYS-223
4.8
4.3
-17.4
12.2
94.7
97.6
25.0
LYS-223
ASP-224
7.2
7.0
-1.2
0.4
99.5
106.9
4.7
ASP-224
ILE-225
5.4
5.3
-4.0
-2.7
34.5
39.2
29.4
ILE-225
GLN-226
4.7
4.8
14.4
-5.1
113.4
115.9
-33.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees