Pyruvate Kinase, M2 Isozyme

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-113   LYS-114  5.6 5.9 -1.2 -8.6 64.8 73.1 46.5
 LYS-114   GLY-115  3.1 2.7 -11.9 -6.0 61.7 62.3 56.3
 GLY-115   PRO-116  1.5 1.9 19.9 -7.0 84.3 93.1 1.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-215   ASP-216  12.1 11.7 33.3 -33.9 134.6 132.3 -10.3
 ASP-216   LEU-217  13.5 12.6 -8.9 -12.5 31.6 31.9 88.9
 LEU-217   PRO-218  10.6 9.6 -8.7 -11.3 69.2 85.8 -4.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees