Epidermal Growth Factor Receptor
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LYS-185
LEU-186
10.5
12.0
39.3
8.5
92.1
80.8
0.1
LEU-186
THR-187
7.1
8.3
26.2
8.0
71.3
53.2
77.1
THR-187
LYS-188
6.3
6.8
-57.5
58.8
86.3
71.9
-28.7
LYS-188
ILE-189
3.4
4.0
-130.2
-93.2
16.1
32.2
-697.1
ILE-189
ILE-190
1.7
5.8
117.2
67.5
134.8
99.8
562.7
ILE-190
CYS-191
5.1
6.1
115.4
-4.6
90.0
71.8
80.4
CYS-191
ALA-192
7.4
9.3
2.5
-19.7
115.8
96.4
62.9
ALA-192
GLN-193
9.8
13.0
-21.7
25.4
117.0
131.2
22.1
GLN-193
GLN-194
10.8
15.1
-13.1
-4.6
145.0
157.4
-96.6
GLN-194
CYS-195
13.6
16.7
12.2
-26.6
21.9
46.8
-61.6
CYS-195
SER-196
11.6
13.3
-1.8
-25.6
109.1
88.6
66.2
SER-196
GLY-197
10.8
11.9
115.9
-154.2
80.0
91.2
-51.2
GLY-197
ARG-198
7.6
8.2
127.4
-55.8
113.1
66.5
-41.7
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
SER-205
ASP-206
17.6
18.5
-56.7
53.3
117.4
124.8
-15.0
ASP-206
CYS-207
15.0
15.3
3.0
2.1
70.6
52.8
-2.1
CYS-207
CYS-208
12.7
14.0
-6.9
20.8
165.7
146.4
63.8
CYS-208
HIS-209
11.7
12.1
2.2
-13.1
64.5
43.7
-3.3
HIS-209
ASN-210
13.0
13.8
0.9
-7.6
82.5
68.8
-27.1
ASN-210
GLN-211
11.4
13.4
4.4
-5.3
42.2
52.2
-8.2
GLN-211
CYS-212
10.0
11.0
7.2
7.9
90.7
108.7
42.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees