Acetylcholinesterase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-320   LEU-321  12.4 12.6 -8.3 10.3 46.9 49.5 29.5
 LEU-321   GLY-322  10.5 10.5 -14.3 9.9 45.8 45.0 58.7
 GLY-322   VAL-323  8.5 8.5 -7.8 13.2 46.1 45.9 -58.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLU-327   GLY-328  8.1 8.6 -14.2 8.4 116.9 120.6 3.7
 GLY-328   SER-329  9.5 10.2 -1.8 9.0 157.8 163.6 130.6
 SER-329   PHE-330  9.7 9.8 -3.7 -4.0 92.8 103.6 -116.7
 PHE-330   PHE-331  13.1 13.2 16.5 -21.8 97.4 96.4 -33.0
 PHE-331   LEU-332  14.6 15.1 8.5 -0.2 42.8 50.9 97.4
 LEU-332   LEU-333  13.9 14.2 -15.0 12.4 143.1 148.1 -117.9
 LEU-333   TYR-334  14.6 14.3 25.3 -16.5 95.7 86.2 -7.1
 TYR-334   GLY-335  18.1 18.0 -24.9 12.3 75.0 81.7 153.4
 GLY-335   ALA-336  18.9 19.3 -1.1 18.3 102.7 99.0 125.6
 ALA-336   PRO-337  17.6 17.5 14.6 -8.6 3.3 5.8 167.3
 PRO-337   GLY-338  18.5 18.1 -3.0 -4.5 111.0 110.5 -109.7
 GLY-338   PHE-339  15.7 15.3 -14.4 20.9 84.3 86.7 -58.7
 PHE-339   SER-340  13.4 13.3 26.6 -23.5 67.6 57.2 -29.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 SER-343   GLU-344  9.9 9.7 -16.1 16.5 132.8 138.1 -8.4
 GLU-344   SER-345  6.8 6.7 2.2 -9.9 45.5 46.9 -148.4
 SER-345   LYS-346  9.8 9.7 16.9 -20.1 72.2 71.6 18.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-397   HIS-398  7.5 7.5 -5.7 12.3 55.1 56.8 -38.0
 HIS-398   ASN-399  11.1 11.1 3.0 -6.9 103.2 109.0 -49.8
 ASN-399   VAL-400  12.2 12.2 -10.5 7.4 62.9 64.7 86.0
 VAL-400   ILE-401  9.9 9.8 25.5 -20.0 57.3 61.3 56.4
 VAL-400   ILE-401  9.9 9.8 25.5 -20.0 57.3 61.3 56.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-400   ILE-401  9.9 9.8 25.5 -20.0 57.3 61.3 56.4
 VAL-400   ILE-401  9.9 9.8 25.5 -20.0 57.3 61.3 56.4
 ILE-401   CYS-402  6.2 6.2 -3.6 10.6 142.9 146.7 195.0
 CYS-402   PRO-403  6.9 7.2 -11.0 -0.9 140.4 141.4 -221.3
 PRO-403   LEU-404  9.5 9.5 12.2 -8.7 116.0 113.6 -20.6
 PRO-403   LEU-404  9.5 9.5 12.2 -8.7 116.0 113.6 -20.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 PRO-403   LEU-404  9.5 9.5 12.2 -8.7 116.0 113.6 -20.6
 PRO-403   LEU-404  9.5 9.5 12.2 -8.7 116.0 113.6 -20.6
 LEU-404   MET-405  7.7 7.6 8.1 -5.5 120.8 121.0 -74.6
 MET-405   HIS-406  4.3 4.3 7.8 -4.3 149.8 151.5 -103.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 CYS-521   VAL-522  7.3 7.6 3.3 -1.0 42.4 41.0 39.8
 VAL-522   PHE-523  9.7 9.8 -11.1 1.5 67.4 74.0 42.5
 PHE-523   TRP-524  12.3 12.6 10.8 -1.3 81.2 86.4 -27.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees