Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-537   ILE-538  4.4 4.6 -14.8 20.5 81.5 77.4 -10.4
 ILE-538   GLY-539  1.2 1.2 -4.2 6.3 76.7 81.5 4.0
 GLY-539   LYS-540  3.0 4.1 18.3 -29.8 149.1 157.3 31.7
 LYS-540   HIS-541  4.6 5.6 -7.0 9.4 90.2 88.0 9.5
 HIS-541   LYS-542  5.7 6.4 10.6 -20.3 164.3 173.0 33.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-544   ILE-545  3.3 3.4 30.5 -15.4 56.1 56.3 17.6
 ILE-545   ASN-546  0.4 0.1 -15.2 -3.3 53.7 48.5 52.3
 ASN-546   LEU-547  3.1 3.4 9.7 -0.5 78.6 78.8 31.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-562   TYR-563  4.4 4.6 24.4 -13.6 139.6 137.6 -35.6
 TYR-563   ALA-564  3.3 2.8 34.6 -28.6 103.4 94.3 14.5
 ALA-564   SER-565  0.4 1.0 -10.1 -5.1 14.8 14.2 38.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees