Asp/glu-Specific Dipeptidyl-Peptidase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-287   THR-288  4.7 3.4 -9.0 -3.0 79.4 80.0 9.1
 THR-288   GLU-289  6.9 5.8 3.5 -0.3 115.2 123.7 -27.8
 GLU-289   TRP-290  4.8 4.2 -2.6 -1.7 132.7 119.0 -19.1
 TRP-290   SER-291  3.0 3.0 -5.5 20.4 125.8 126.7 36.6
 SER-291   GLU-292  6.2 5.6 16.8 -18.1 119.1 119.8 -8.8
 GLU-292   ILE-293  9.2 8.3 -4.0 13.3 63.3 56.7 -13.7
 ILE-293   ASP-294  8.3 8.0 -24.8 15.7 116.9 119.7 -31.3
 ILE-293   ASP-294  8.3 8.0 -24.8 15.7 116.9 119.7 -31.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-293   ASP-294  8.3 8.0 -24.8 15.7 116.9 119.7 -31.3
 ILE-293   ASP-294  8.3 8.0 -24.8 15.7 116.9 119.7 -31.3
 ASP-294   ASN-295  6.8 7.8 -8.5 29.9 146.1 150.3 83.3
 ASN-295   ASN-296  8.1 8.4 5.0 0.2 86.2 90.3 29.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-336   ALA-337  9.0 9.5 -1.4 2.5 123.3 128.1 11.1
 ALA-337   GLN-338  8.6 8.8 -1.3 13.8 61.3 64.9 -12.1
 GLN-338   GLY-339  9.7 10.0 -24.1 15.8 51.7 54.5 15.9
 GLY-339   ALA-340  6.5 7.1 -16.0 8.7 125.9 120.2 -3.8
 ALA-340   ASN-341  4.6 4.4 4.3 -3.3 82.0 73.3 22.8
 ASN-341   TRP-342  7.6 6.6 -11.2 -6.9 35.8 41.4 70.2
 TRP-342   ALA-343  7.6 7.8 8.1 3.7 89.7 108.4 -22.9
 ALA-343   ILE-344  5.4 4.4 -19.5 17.1 130.3 127.3 -19.5
 ILE-344   ARG-345  7.7 5.4 10.6 0.0 112.9 103.6 -1.3
 ARG-345   ARG-346  11.0 9.0 -15.4 27.8 40.1 30.7 -51.0
 ARG-346   ARG-347  10.1 8.8 22.9 -16.5 92.9 98.6 -17.7
 ARG-347   SER-348  8.1 7.2 -5.4 -1.6 134.5 137.7 -4.3
 SER-348   LEU-349  10.3 9.3 6.1 -8.0 56.2 62.1 -18.1
 LEU-349   ARG-350  7.5 6.6 20.3 -7.0 30.1 25.2 67.0
 ARG-350   GLU-351  9.1 8.0 -1.5 -1.6 84.6 86.4 10.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-380   LYS-381  8.5 7.6 14.1 -9.9 142.5 148.2 -5.7
 LYS-381   ALA-382  7.7 7.0 -7.2 -1.4 89.1 84.9 1.8
 ALA-382   ILE-383  4.1 3.6 -1.8 13.6 127.5 126.3 18.3
 ILE-383   GLU-384  4.2 2.9 -9.9 17.1 69.6 64.7 -30.9
 GLU-384   GLY-385  7.1 5.8 -19.8 2.5 30.9 36.5 53.1
 GLY-385   ARG-386  5.1 4.0 10.4 10.6 81.3 81.6 17.7
 ARG-386   GLN-387  4.0 3.1 -5.8 5.8 133.2 120.0 9.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-540   ALA-541  6.9 7.2 -3.6 12.3 120.7 113.6 5.8
 ALA-541   PHE-542  4.6 4.5 -18.2 -3.4 58.8 47.5 62.6
 PHE-542   ASP-543  2.8 2.8 -28.9 3.2 48.7 41.7 80.1
 ASP-543   ALA-544  6.0 5.5 6.1 4.2 76.2 78.8 -15.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees