Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-85   GLY-86  7.4 6.8 -8.2 0.0 72.8 68.1 5.2
 GLY-86   PRO-87  3.9 3.7 24.2 -16.2 85.1 91.8 11.6
 PRO-87   GLU-88  1.0 0.3 -83.3 31.1 33.4 33.2 116.3
 GLU-88   ILE-89  3.9 3.3 23.9 -26.5 91.8 79.3 -12.4
 ILE-89   ARG-90  6.6 6.6 8.5 5.2 110.1 114.3 -3.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-187   ALA-188  5.1 4.0 -43.5 7.2 112.1 118.3 -46.8
 ALA-188   VAL-189  5.6 4.9 23.1 -9.6 102.2 112.6 21.2
 VAL-189   SER-190  3.8 3.8 -38.7 10.3 62.1 56.6 57.9
 SER-190   ALA-191  1.0 0.6 -16.2 5.0 27.9 33.3 19.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees