Fibroblast Growth Factor Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASP-247   VAL-248  8.3 8.0 23.6 -14.4 82.9 88.9 0.8  VAL-248   VAL-249  5.5 5.0 19.7 -26.3 131.3 130.0 34.0  VAL-249   GLU-250  4.9 4.5 -9.7 24.0 102.9 102.0 39.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees