Cgmp-Specific 3',5'-Cyclic Phosphodiesterase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-649   ALA-650  3.4 3.3 3.3 -5.0 95.9 95.2 0.3
 ALA-650   LEU-651  2.6 2.7 3.1 -1.0 132.0 129.9 -1.3
 LEU-651   SER-652  5.9 5.9 2.2 -2.5 161.5 162.9 2.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-680   MET-681  13.9 8.3 -29.4 21.3 139.0 84.5 1.2
 MET-681   GLU-682  12.5 4.9 -28.7 7.2 90.1 35.5 12.7
 GLU-682   HIS-683  8.8 4.7 -178.6 75.1 69.5 97.1 17.3
 HIS-683   HIS-684  7.3 6.6 -154.6 26.7 86.9 116.7 -19.8
 HIS-684   HIS-685  4.3 4.1 164.8 64.2 84.2 129.3 -85.3
 HIS-685   PHE-686  5.0 2.3 162.2 39.4 123.8 121.9 169.4
 PHE-686   ASP-687  6.5 5.5 -39.3 2.4 121.0 123.1 -36.8
 ASP-687   GLN-688  8.4 7.6 2.6 9.5 92.5 88.4 -7.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees