Proto-Oncogene Tyrosine-Protein Kinase Src

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-255   ALA-256  12.3 13.7 -176.3 -106.3 18.2 25.7 223.3
 ALA-256   LYS-257  12.7 13.1 31.1 73.3 83.9 127.5 -51.8
 LYS-257   ASP-258  9.8 12.4 -25.6 -164.4 39.3 100.1 -155.9
 ASP-258   ALA-259  10.4 10.3 177.7 -15.9 99.9 31.2 43.2
 ALA-259   TRP-260  9.6 9.2 131.5 -75.3 42.4 50.8 52.2
 TRP-260   GLU-261  9.9 9.8 -60.8 -21.7 111.7 129.0 -36.4
 GLU-261   ILE-262  6.2 7.4 -41.4 32.5 72.9 81.8 15.4

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees