Vitamin D Hydroxylase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-145   PRO-146  9.3 9.8 8.0 3.2 34.4 38.2 37.8
 PRO-146   VAL-147  7.6 8.1 2.7 -16.5 45.9 50.3 -32.5
 VAL-147   GLN-148  9.7 9.7 13.5 -1.0 103.6 111.7 3.4
 GLN-148   VAL-149  9.9 9.8 -1.1 -6.0 91.1 87.2 5.6
 VAL-149   ILE-150  6.3 6.1 8.2 8.1 18.6 28.5 66.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-223   GLU-224  7.8 9.6 -10.7 15.7 98.4 90.1 21.9
 GLU-224   GLU-225  4.6 6.2 -3.1 -9.2 136.8 132.2 -49.3
 GLU-225   LEU-226  3.0 4.7 2.2 2.7 27.6 18.0 18.4
 LEU-226   VAL-227  5.3 6.5 -4.5 -9.8 104.8 108.1 -55.6
 VAL-227   ALA-228  5.7 6.2 12.4 2.9 72.7 90.7 36.9
 ALA-228   MET-229  2.8 2.8 -9.2 -0.1 154.1 151.1 -36.5
 MET-229   ALA-230  1.4 1.8 3.3 -4.1 45.1 39.5 0.7
 ALA-230   MET-231  4.6 4.2 0.2 1.0 81.9 88.7 15.8
 MET-231   LEU-232  5.8 5.1 9.4 -10.1 58.6 71.4 -8.2
 LEU-232   LEU-233  4.1 3.3 1.0 11.6 9.9 6.1 87.6
 LEU-233   LEU-234  2.8 2.2 5.1 -8.3 64.3 63.4 -12.2
 LEU-234   ILE-235  6.3 5.8 -6.5 2.3 98.5 84.2 -29.0
 ILE-235   ALA-236  8.2 7.8 -4.4 -14.3 136.6 122.0 -75.3
 ALA-236   GLY-237  6.7 7.2 6.3 -19.6 26.0 6.9 -74.5
 GLY-237   HIS-238  6.4 5.9 3.6 12.7 74.4 59.6 30.1
 HIS-238   GLU-239  10.2 8.9 -54.6 73.8 96.3 101.5 40.9
 GLU-239   THR-240  11.8 12.2 -49.5 56.2 116.7 121.7 24.9
 THR-240   THR-241  10.9 11.6 20.8 -12.6 2.2 9.3 46.4
 THR-241   VAL-242  9.7 9.8 -0.9 -2.5 118.3 120.1 24.6
 VAL-242   ASN-243  12.4 12.5 -13.2 14.6 103.3 108.1 -3.7
 ASN-243   LEU-244  14.9 15.1 -7.6 6.4 128.7 130.8 -22.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees