Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-631   LYS-632  15.2 15.3 0.7 -1.6 133.1 124.9 -2.1
 LYS-632   ILE-633  12.7 12.4 -2.6 1.5 101.1 101.2 -6.5
 ILE-633   ALA-634  9.1 8.7 4.3 -2.4 148.0 153.7 -1.3
 ALA-634   ASP-635  6.8 6.6 -7.6 -19.9 102.1 96.3 -11.3
 ASP-635   PHE-636  3.5 3.1 -32.1 -2.3 100.3 122.3 -19.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-655   LEU-656  11.8 12.9 38.0 26.7 113.2 89.9 5.5
 LEU-656   PRO-657  9.1 12.4 -39.9 16.0 61.2 82.6 25.2
 PRO-657   VAL-658  7.1 8.8 -85.6 -3.1 12.7 41.2 106.2
 VAL-658   LYS-659  8.4 9.4 8.1 4.6 141.8 143.1 -6.3
 LYS-659   TRP-660  7.6 8.3 0.2 1.6 91.8 83.2 0.6
 TRP-660   MET-661  4.0 4.9 -8.6 19.7 82.8 88.7 3.2
 MET-661   ALA-662  4.1 4.7 -1.1 3.1 26.9 24.6 -3.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees