Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-714   GLY-715  7.3 6.9 -9.9 -14.3 73.4 76.0 35.1
 GLY-715   PRO-716  3.7 3.1 9.3 -15.0 96.1 114.7 5.1
 PRO-716   GLU-717  1.8 2.1 -97.7 79.5 35.0 28.2 61.4
 GLU-717   ILE-718  4.7 4.4 9.3 -3.9 95.9 91.3 -15.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-813   ALA-814  9.8 10.2 -20.3 16.0 37.0 37.6 -52.6
 ALA-814   VAL-815  10.8 9.8 46.8 -33.6 135.0 135.6 -3.8
 VAL-815   ASP-816  8.6 7.7 -30.1 30.3 14.1 15.9 -39.6
 ASP-816   LEU-817  9.4 9.1 -24.1 18.0 56.0 50.4 51.6
 LEU-817   PRO-818  6.3 6.1 -20.7 -4.8 52.8 65.9 66.1
 PRO-818   ALA-819  4.7 4.4 -7.7 -5.0 111.6 104.9 -8.7
 ALA-819   VAL-820  4.2 3.0 3.9 4.0 98.2 130.5 -29.6
 VAL-820   SER-821  1.4 1.2 -28.4 -17.2 78.5 67.5 35.8
 SER-821   GLU-822  2.5 2.5 -16.7 18.0 22.8 37.2 -7.2
 GLU-822   LYS-823  4.5 4.1 -6.8 7.0 93.7 103.8 -2.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees