Epidermal Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-744   VAL-745  4.9 3.6 9.2 57.5 9.0 11.3 176.3  VAL-745   ASP-746  4.3 3.3 -2.9 59.0 114.7 125.5 103.2  ASP-746   ASN-747  2.9 4.2 -131.5 80.3 165.8 141.6 -131.4  ASN-747   PRO-748  2.4 2.6 -10.9 -3.4 115.8 98.3 -4.9  PRO-748   HIS-749  0.4 0.8 4.4 -1.3 80.8 88.9 -11.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees