/Hiv-1 Protease (Isolate Hxb2)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-30   THR-31  9.3 9.4 8.4 9.6 30.1 30.1 65.3
 THR-31   VAL-32  6.7 6.7 9.9 -3.1 90.2 91.0 -35.5
 VAL-32   LEU-33  4.2 4.2 -4.5 9.3 149.7 145.0 52.7
 LEU-33   GLU-34  1.4 1.3 -28.0 2.2 102.3 94.3 18.9
 GLU-34   GLU-35  3.0 3.6 16.3 24.7 132.8 122.6 -191.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-38   PRO-39  8.2 7.4 16.3 -3.8 143.0 149.3 -20.7
 PRO-39   GLY-40  10.9 9.5 22.8 -59.1 129.3 144.9 245.0
 GLY-40   ARG-41  8.5 8.5 7.5 18.0 122.4 98.4 -83.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-58   TYR-59  1.9 1.8 -8.9 -0.7 106.1 108.3 -46.6
 TYR-59   ASP-60  2.0 2.1 -11.7 -1.7 110.5 99.8 -163.4
 ASP-60   GLN-61  4.4 4.8 -163.2 -171.3 77.2 75.7 -92.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-74   VAL-75  5.9 5.8 -17.6 11.2 161.3 157.1 -65.1
 VAL-75   LEU-76  3.6 3.4 -5.9 6.2 76.8 78.1 13.9
 LEU-76   VAL-77  2.1 2.4 10.1 -9.6 43.0 37.7 62.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-84   ILE-85  6.8 6.6 -1.6 -3.8 133.6 129.8 75.2
 ILE-85   GLY-86  8.8 8.6 10.2 -33.7 62.7 70.3 -102.1
 GLY-86   ARG-87  10.9 10.9 -6.4 1.1 100.7 117.1 -69.0
 ARG-87   ASN-88  14.1 14.0 23.8 -25.0 60.2 45.5 123.6
 ASN-88   LEU-89  12.3 12.2 5.9 -3.7 112.9 114.9 19.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees