Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-86   PRO-87  4.6 4.6 -10.8 2.5 96.7 83.0 1.5
 PRO-87   GLU-88  0.9 1.1 70.3 -13.0 35.3 34.5 132.4
 GLU-88   ILE-89  3.1 3.7 -17.7 17.5 82.6 89.7 -22.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-174   ARG-175  14.0 14.3 -13.6 9.2 33.8 49.8 11.9
 ARG-175   GLY-176  12.4 12.1 32.8 -30.5 82.5 75.5 -1.5
 GLY-176   VAL-177  8.6 8.3 13.8 -2.9 122.7 132.2 -10.6
 VAL-177   ASN-178  7.4 7.3 19.0 -5.1 92.6 96.8 26.4
 ASN-178   LEU-179  4.7 5.0 26.8 -15.4 106.5 106.2 -1.2
 LEU-179   PRO-180  6.2 7.0 -1.3 -13.3 70.3 56.7 -15.6
 PRO-180   GLY-181  5.3 6.4 -154.5 -150.0 94.7 89.5 44.7
 GLY-181   CYS-182  8.3 10.1 -50.3 0.3 125.9 157.3 -79.0
 CYS-182   ASP-183  9.5 10.1 152.9 -139.7 27.3 51.9 33.3
 ASP-183   VAL-184  9.4 10.4 23.5 3.4 43.6 37.6 55.2
 VAL-184   ASP-185  7.3 7.8 2.4 -38.4 25.3 33.1 -92.5
 ASP-185   LEU-186  8.0 8.7 -33.2 52.8 120.9 142.4 51.1
 LEU-186   PRO-187  4.4 5.5 27.4 -1.1 64.6 61.1 11.0
 PRO-187   ALA-188  4.1 4.8 -3.2 -5.2 69.6 65.8 -0.2
 ALA-188   VAL-189  5.7 5.8 8.2 1.7 72.8 78.5 40.3
 VAL-189   SER-190  4.6 4.6 23.0 -5.7 51.0 60.3 22.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees