Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-193   SER-194  2.7 2.9 -1.1 -8.3 49.9 54.9 16.9
 SER-194   ASP-195  0.9 0.9 19.5 -4.5 75.0 73.6 30.3
 ASP-195   ALA-196  3.5 3.7 -24.6 -3.1 68.3 73.7 24.0
 ALA-196   GLN-197  5.5 5.5 6.3 -4.2 35.5 37.9 -0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-330   SER-331  0.2 0.9 8.2 24.5 93.4 96.6 -15.8
 SER-331   PRO-332  3.4 3.2 -21.4 -7.4 17.3 19.0 100.7
 PRO-332   ASP-333  4.3 4.6 5.3 -44.9 95.4 98.1 9.4
 ASP-333   VAL-334  7.4 7.4 -18.5 2.4 82.3 75.1 25.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-463   GLY-464  7.2 8.1 -2.1 89.4 138.2 132.8 191.2
 GLY-464   ARG-465  4.7 5.8 -52.8 22.4 105.7 158.1 -89.9
 ARG-465   TYR-466  4.4 5.8 -74.5 21.3 108.7 114.4 -75.4
 TYR-466   GLU-467  4.5 4.7 39.5 -30.4 29.3 20.3 39.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees